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recombinant interleukin-4
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T-cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B-cells and enhancing their ability to present antigens to T-cells. As a potential immunotherapeutic agent, recombinant IL-4 also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | B Cell Proliferating Factor B-Cell Growth Factor B-Cell Stimulating Factor B-Cell Stimulatory Factor 1 Mast Cell Growth Factor-2 recombinant human IL-4 T-Cell Growth Factor 2 | |
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| Abbreviations: | | BCGF BCSF 1 IL-4 MCGF 2 rhIL-4 | |
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