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RFA on the Development of Mouse Phenotypic Screens for Heart, Lung, and Blood Diseases The aim of this RFA is to solicit research grant applications for the development of phenotypic screening methods in the mouse for heart, lung, and blood diseases and sleep disorders. The purpose of the RFA is to stimulate research on the phenotypic screening of mice for heart, lung, blood and sleep disorders in order to accelerate the pace at which mice with heritable disorders that are models of human disease produced through either targeted or random mutagenesis are made available to the research community for further investigation or application. This RFA will support investigators to (1) develop mouse screening and phenotype characterization protocols, particularly those that can be used for high throughput analysis of mouse phenotypes; (2) provide for the systematic validation of these screening protocols against normal inbred mouse strains and genetically altered mouse strains that approximate the disease of interest; and (3) provide for the timely dissemination of information and methodologies to the scientific community. $4.5 million is available for the first year of this initiative, which should support approximately 10 projects for up to four years duration. The application receipt date is September 15, 1999, and the anticipated award date is July 1, 2000. Additional information about this RFA can be found at |
