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Colon and Rectal Cancer Trial Results

Sigmoidoscopy Proves to Be Effective Screening Tool for Colorectal Cancer
(Posted: 06/07/2012) - In a large randomized trial involving healthy men and women aged 55 to 74, sigmoidoscopy substantially reduced the incidence of and mortality from colorectal cancer.

Colonoscopy Reduces Risk of Death from Colorectal Cancer in High-Risk Patients
(Posted: 03/19/2012) - Long-term results from the National Polyp Study confirm that removing precancerous adenomas not only reduces the risk of colorectal cancer but also reduces the number of deaths from the disease by more than half. The findings appeared February 23, 2012, in the New England Journal of Medicine.

Study Shows Aspirin Reduces Colorectal Cancer in Those at High Risk
(Posted: 12/02/2011) - Findings from the first large clinical trial of its kind indicate that taking high doses of aspirin daily for at least 2 years substantially reduces the risk of colorectal cancer among people at increased risk of the disease.

Cetuximab Combined with Oxaliplatin-Based Chemotherapy May Not Be Effective First-Line Treatment for Metastatic Colorectal Cancer
(Posted: 08/30/2011) - In a randomized phase III trial, the addition of the targeted therapy cetuximab to oxaliplatin and fluoropyrimidine chemotherapy did not prolong survival or time to disease progression of patients with advanced colorectal cancer. The results were published on June 5, 2011 in The Lancet.

Colorectal Cancer Trials Support Gene Testing for Two Drugs
(Posted: 11/12/2008, Updated: 07/08/2011) - A trio of 2008 studies adds to the growing evidence that patients with colorectal cancer should have their tumors tested for genetic mutations prior to starting therapy with cetuximab (Erbitux®) or panitumumab (Vectibix®).

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