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U.S. Department of Health and Human Services

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Viral Hepatitis Therapies

Click on drug brand name for additional information.

Approved Treatments for Hepatitis B
Brand Name Generic Names Manufacturer Name Indication
Baraclude entecavir Bristol-Myers Squibb chronic hepatitis B virus infection with evidence of active viral replication
Epivir-HBV lamivudine GlaxoSmithKline chronic hepatitis B associated with
hepatitis B viral replication and active liver inflammation
Hepsera adefovir dipivoxil Gilead Sciences chronic hepatitis B in patients ≥12 years of age
Intron A interferon alpha-2b Schering chronic hepatitis B in patients 1 year of age or older with compensated liver disease
Pegasys pegylated interferon Roche treatment of adult patients with HBeAg positive and HBeAg negative chronic hepatitis B who have compensated liver disease and evidence of viral replication and liver inflammation
Tyzeka telbivudine Novartis chronic hepatitis B in adult patients with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease
Viread tenofovir Gilead Sciences chronic hepatitis B in adults.

 

Approved Treatments for Hepatitis C
Brand Name Generic Names Manufacturer Name Indication
Incivek telaprevir Vertex Pharmaceuticals in combination with peginterferon alfa and ribavirin, for the treatment of genotype 1 chronic hepatitis C (CHC) in adult patients with compensated liver disease, including cirrhosis, who are treatment-naïve or who have been previously treated with interferon-based treatment, including prior null responders, partial responders, and relapsers
Victrelis boceprevir Merck & Co. treatment of chronic hepatitis C (CHC) genotype 1 infection, in combination with peginterferon alfa and ribavirin, in adult patients (≥18 years of age) with compensated liver disease, including cirrhosis, who are previously untreated or who have failed previous interferon and ribavirin therapy.
Pegasys pegylated interferon Roche treatment of adults with chronic hepatitis C virus infection who have compensated liver disease and have not been previously treated with interferon alpha
CoPegus ribavirin Roche use in combination with Pegasys or with Roferon for the treatment of adults with chronic hepatitis C virus infection who have compensated liver disease and have not been previously treated with interferon alpha
Pegintron pegylated interferon alpha-2b Schering

in combination with rebetol, is indicated for the treatment of chronic hepatitis C in patients 3 years of age and older with compensated liver disease

 

use alone for the treatment of chronic hepatitis C in patients with compensated liver disease previously untreated with interferon alpha and who are at least 18 years of age and intolerant to ribavirin

Intron A interferon alpha-2b Schering treatment of chronic hepatitis C in patients 18 years of age or older with compensated liver disease who have a history of blood or blood-product exposure and/or are HCV antibody positive
Rebetol ribavirin Schering use in combination with Pegintron for treatment of chronic hepatitis C in patients with compensated liver disease who have not been previously treated with interferon alpha and are at least 18 years of age
Roferon interferon alpha-2a Roche treatment of chronic hepatitis C in patients 18 years of age or older
Infergen interferon aphacon-1 Three Rivers Pharma treatment of chronic hepatitis C in patients 18 years of age or older with compensated liver disease who have anti-HCV serum antibodies and/or HCV RNA
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