Trans-NIH Mouse Initiative
*Funding Opportunitites

RFA on Phenotypic Characterization of Sleep in Mice

The primary goal of RFA is to advance our understanding of sleep and wakefulness by developing improved molecular, cellular, and systems approaches to investigate sleep and circadian phenotypes in mice. Better and more extensively-characterized mouse models should help in determining the genetic underpinnings of sleep and wakefulness, elucidating the physiological role of sleep, and developing new directions for the treatment of sleep disorders. Establishing inbred mice strains as a platform for sleep studies will facilitate the use of targeted and transgenic gene modification approaches in sleep research, lead to a refinement in the definition of sleep state in molecular and genomic terms, and advance our understanding of normal sleep phenotypes.

Additional information about this RFA can be found at