Trans-NIH Mouse Initiative
*Funding Opportunitites


RFA on A Data Coordination Center for the Knockout Mouse Project (KOMP) (HG -05-08)

Letters of Intent Due: October 20, 2005

Applications Due: November 22, 2005


The purpose of this RFA is to solicit applications for a project to develop and implement the Data Coordination Center (DCC) component of the KOMP research network. The DCC will be expected to obtain data from each of the participating KOMP Research Network projects -- the repatriation/repository effort, the mutant ES cell or mouse production pipelines and, to a lesser extent, from the developmental efforts.  These data should include, but are not limited to, a variety of information types relating to the production status of mutants (from vector design through production of mutant ES cells or mutant mice), development of improved C57BL/6 ES cell lines, and the locations of ES cells or mice (from both repatriation and production efforts) in NIH-supported repositories.  The DCC will compile and track several lists of mouse genes – those that have been mutated and for which ES cells or mice are available to investigators, those that have entered into the mutation production pipeline and their status in the pipeline, and those that remain to be taken up by the pipeline. The DCC will establish systems that will allow the KOMP Research Network projects, NIH staff, advisors, and the public to have access to this information. 

This funding opportunity will use the NIH U01 cooperative agreement award mechanism. A total of $0.5 million per year in total costs for 5 years is to be awarded through this RFA. It is anticipated that 1 award will be funded in July 2006 for five years. The full text of the RFA is available at: .