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Clinical Trials
The National Heart, Lung, and Blood Institute (NHLBI) is strongly committed to supporting research aimed at preventing and treating heart, lung, and blood diseases and conditions and sleep disorders.
NHLBI-supported research has led to many advances in medical knowledge and care. For example, this research has uncovered some of the causes of various diseases and conditions, as well as ways to prevent, diagnose, or treat them.
The NHLBI continues to support research aimed at learning more about various diseases and conditions, including overweight and obesity. For example, NHLBI-supported research on overweight and obesity includes studies that:
- Explore how abdominal obesity affects the human heart and its function
- Examine whether environmental strategies and behavioral changes help reduce overeating in obese children
- Compare the effect of three types of beverages—sugar-sweetened, artificially sweetened, and unsweetened—on heart and blood vessel disease risk factors
- Explore how different diets and physical activities affect overweight and obesity
- Look at how family behaviors influence overweight and obesity in children
Much of this research depends on the willingness of volunteers to take part in clinical trials. Clinical trials test new ways to prevent, diagnose, or treat various diseases and conditions.
For example, new treatments for a disease or condition (such as medicines, medical devices, surgeries, or procedures) are tested in volunteers who have the illness. Testing shows whether a treatment is safe and effective in humans before it is made available for widespread use.
By taking part in a clinical trial, you can gain access to new treatments before they're widely available. You also will have the support of a team of health care providers, who will likely monitor your health closely. Even if you don't directly benefit from the results of a clinical trial, the information gathered can help others and add to scientific knowledge.
If you volunteer for a clinical trial, the research will be explained to you in detail. You'll learn about treatments and tests you may receive, and the benefits and risks they may pose. You'll also be given a chance to ask questions about the research. This process is called informed consent.
If you agree to take part in the trial, you'll be asked to sign an informed consent form. This form is not a contract. You have the right to withdraw from a study at any time, for any reason. Also, you have the right to learn about new risks or findings that emerge during the trial.
For more information about clinical trials related to overweight and obesity, talk with your doctor. You also can visit the following Web sites to learn more about clinical research and to search for clinical trials:
- http://clinicalresearch.nih.gov
- www.clinicaltrials.gov
- www.nhlbi.nih.gov/studies/index.htm
- www.researchmatch.org
For more information about clinical trials for children, visit the NHLBI's Children and Clinical Studies Web page.
Featured Video
Obesity happens one pound at a time. So does prevention.
Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. To find clinical trials that are currently underway for Overweight and Obesity, visit www.clinicaltrials.gov.
May 28, 2012
NIH Media Availability: NIH-funded study examines use of mobile technology to improve diet and physical activity behavior
A new study, supported in part by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, suggests that a combination of mobile technology and remote coaching holds promise in encouraging healthier eating and physical activity behavior in adults. The study focused on the best way to change multiple health behaviors.
Hear people talk about their challenges and successes reaching and maintaining a healthy weight on the HBO Documentary Films series, “The Weight of the Nation,” which premiered in May 2012.
The film series spotlights the science behind obesity and how it affects the health of the nation. Watch the series to learn how citizens, groups, and policymakers are working to make a difference in their communities. The films stream free on the HBO Web site.
To learn more about the film series and related public awareness campaign, including how to host a local screening go to www.nih.gov/health/
NIHandweightofthenation.
The NHLBI updates Health Topics articles on a biennial cycle based on a thorough review of research findings and new literature. The articles also are updated as needed if important new research is published. The date on each Health Topics article reflects when the content was originally posted or last revised.
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