Chemistry Programs & Projects | |
|
Development of Reference Methods and Reference Materials for the Determination of Hormones in Human Serum
Last Updated Date: 10/05/2012 Hormones are chemical messengers that regulate many life functions, and deviations from normal levels can indicate serious health problems. … more
Development of a Standard Reference Material for Metabolites in Plasma
Last Updated Date: 10/05/2012 Metabolomics is a relatively new field that builds upon work in genomics and proteomics. Metabolomics can provide a unique perspective on the … more
Reference Measurement Procedures and Materials for Creatinine
Last Updated Date: 10/05/2012 Chronic kidney disease (CKD) is a growing problem in the U.S., and current estimates suggest that more than 20 million Americans are affected by … more
Metallomics: A Multidisciplinary Approach for the Qualitative and Quantitative Determination of Proteins and Metalloproteins Used as Health and Disease Markers
Last Updated Date: 10/05/2012 As healthcare shifts from management of disease to management of health, there will be a necessary shift toward development of quantitative health … more
Development of Proteomics-Based Methods for Protein Quantification
Last Updated Date: 10/05/2012 NIST is developing methods for the quantification of clinically-relevant protein biomarkers by mass spectrometry. Some methods are intended to … more
Expression of Stable Isotopically Labeled Proteins for Use as Internal Standards for Mass Spectrometric Quantitation of Clinical Protein Biomarkers
Last Updated Date: 10/05/2012 Proteins are of significant interest as potential indicators (biomarkers) of health or disease. Clinical methods employed to measure these … more
Improving Measurement Quality in Clinical Proteomics
Last Updated Date: 10/05/2012 Through collaboration with academic and government institutes, NIST is critically evaluating and attempting to improve measurement quality in … more
Development of Reference Methods and Reference Materials for the Determination of Cardiac Troponin I in Human Serum
Last Updated Date: 10/05/2012 Cardiac troponin I (cTnI) is considered the 'gold standard' for the diagnosis of myocardial infarction and the assessment of cardiac … more
Development of a Reference Measurement Procedure for C-Reactive Protein in Human Serum
Last Updated Date: 10/05/2012 C-reactive protein (CRP) levels in serum or plasma have been used as an indicator of inflammation and infection. Recent evidence also suggests … more
Development of an Amino Acid (in Solution) Standard Reference Material
Last Updated Date: 10/05/2012 Amino acids are the sequential components of proteins and many are essential to our physiological well-being. Their quantification by the … more
Chromatographic Separation of Unfolded Proteins for Protein Quantification
Last Updated Date: 10/05/2012 NIST is developing methods for the quantification of protein biomarkers by mass spectrometry (MS). Stable isotope labeling of proteins/peptides … more
Development of Reference Methods and Reference Materials for Proteins
Last Updated Date: 10/05/2012 A number of proteins show promise as potential markers of health or disease, and commercial assays are being developed for these proteins. For … more
Optimization of the Standard Addition Method (SAM) Using
Last Updated Date: 10/05/2012 The standard addition method (SAM) was first described by oceanographers in 1955 to overcome matrix effects in the determination of strontium in … more
High-Precision Isotopic Reference Materials
Last Updated Date: 10/05/2012 Recent innovative advances in the design and manufacture of isotope ratio mass spectrometers (IRMS) have revolutionized the study of natural and … more
Mercury Vapor Pressure Correlation
Last Updated Date: 10/05/2012 An apparent difference between the historical mercury vapor concentration equations used by the mercury atmospheric measurement community and a … more |
Contact
General Information:301-975-NIST (6478) inquiries@nist.gov 100 Bureau Drive, Stop 1070 Gaithersburg, MD 20899-1070 |