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Who Is at Risk for Sickle Cell Anemia?

Sickle cell anemia is most common in people whose families come from Africa, South or Central America (especially Panama), Caribbean islands, Mediterranean countries (such as Turkey, Greece, and Italy), India, and Saudi Arabia.

In the United States, it's estimated that sickle cell anemia affects 70,000–100,000 people, mainly African Americans. The disease occurs in about 1 out of every 500 African American births. Sickle cell anemia also affects Hispanic Americans. The disease occurs in more than 1 out of every 36,000 Hispanic American births.

More than 2 million Americans have sickle cell trait. The condition occurs in about 1 in 12 African Americans.

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Living With and Managing Sickle Cell Disease (Nicholas)


Sickle Cell Anemia Clinical Trials

Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. To find clinical trials that are currently underway for Sickle Cell Anemia, visit www.clinicaltrials.gov.

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Visit Children and Clinical Studies to hear experts, parents, and children talk about their experiences with clinical research.


Sickle Cell Anemia in the News

October 13, 2011
NIH-funded researchers correct sickle cell disease in adult mice
National Institutes of Health-funded scientists have corrected sickle cell disease in adult laboratory mice by activating production of a special blood component normally produced before, but not after, birth.

View all Sickle Cell Anemia Press Releases


Sickle Cell Disease Story of Success

NHLBI-supported research has helped reduce the burden of sickle cell disease. Learn more about how this research has benefited Tiffany McCoy and others who are living with sickle cell disease in the NHLBI’s stories of success.

 
September 28, 2012 Last Updated Icon

The NHLBI updates Health Topics articles on a biennial cycle based on a thorough review of research findings and new literature. The articles also are updated as needed if important new research is published. The date on each Health Topics article reflects when the content was originally posted or last revised.

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