Pellagra is a disease that occurs when a person does not get enough niacin (one of the B complex vitamins) or tryptophan (an amino acid).
Pellagra is caused by having too little niacin or tryptophan in the diet. It can also occur if the body fails to absorb these nutrients. It may develop after gastrointestinal diseases or with alcoholism.
The disease is common in parts of the world where people have a lot of corn in their diet.
Symptoms of pellagra include:
Vitamin B3 deficiency; Deficiency - niacin
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Kumar N. Neurologic presentation of nutritional deficiencies. Neurol Clin. 2010;28:107-170.
Updated by: Linda Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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