This page is for historical and reference purposes only. Updates to content and links will not be maintained. Current information about NIDDK's Kidney, Urological and Hematology programs can be found at http://www2.niddk.nih.gov/Research/ScientificAreas/Kidney/, http://www2.niddk.nih.gov/Research/ScientificAreas/Urology/ and http://www2.niddk.nih.gov/Research/ScientificAreas/Hematology/.
The American Society of Nephology met in San Diego, CA on December 10-13, 2011.
Meeting Poster (PDF, 371 KB) Printer friendly version of the contents on this page
NIDDK Hematology Program
In 1950 the “Omnibus Medical Research Act” established a new Institute at NIH to support basic and clinical research relevant to a broad range of medical subspecialty areas, including hematology.Beginning in the early 1950s this new Institute, the National Institute of Arthritis and Metabolic Diseases (NIAMD), began to award grants for support of research on “erythrocyte production, turnover, and metabolism; erythropoietin; hemoglobin; iron, B12, and folate metabolism; hematopoiesis and bone marrow grafts; transplant immunology; immune-hematology; and leukocyte cell biology.”
In 1972, the institute’s name was changed to the National Institute of Arthritis, Metabolism, and Digestive Diseases (NIAMDD) and subsequently in 1986, as NIH grew and new institutes were established, changed again to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Throughout its history, however, the Institute has maintained its commitment to supporting leading edge hematology research in areas defined from the beginning, working in parallel with blood diseases programs in the National Cancer Institute, NCI, and the National Heart Institute, which subsequently became the National Heart, Lung, and Blood Institute, NHLBI.
NIDDK’s 60th anniversary year provides an occasion to highlight the Institute’s many contributions to the support of academic and research hematology throughout its history. The NIDDK Hematology Program has been privileged to have been a source of long-term support for the research and training activities of a distinguished group of hematology academicians and researchers, including 23 ASH presidents.
60 Years of Advancing Research to Improve Health
Long-Term NIDDK Hematology Research Grantees (List of Grantees Timeline)
1950s
GEORGE E CARTWRIGHT, MD
University of Utah
1955-1983
TRAINING GRANT IN HEMATOLOGY
INVESTIGATIONS IN HEMATOLOGY
HEREDITARY HEMOCHROMATOSIS
WILLIAM B CASTLE, MD
Boston City Hospital, Harvard University
1954-1967
ERYTHROPOIETIC REGULATION
AMOZ L CHERNOFF, MD
University of Tennessee
1957-1971
BIOCHEMICAL AND GENETIC STUDIES OF HEMOGLOBIN
JANE F DESFORGES, MD
Boston City Hospital, Tufts University
1956-1972
EFFECT OF AGING ON RED CELL MEMBRANES
CLEMENT A FINCH, MD
University of Washington
1957-1986
HEMATOLOGY AND NUTRITIONAL ANEMIAS TRAINING GRANT
FRANK H GARDNER, MD
Harvard University
Presbyterian Hospital, University of Pennsylvania
1954-1973
RED CELL PRODUCTION AND DESTRUCTION
JOHN W HARRIS, MD
Case Western Reserve University
1955-1998
STUDIES OF ERYTHROCYTE PRODUCTION & DESTRUCTION
A STUDY OF NUTRITIONAL AND HEMOLYTIC ANEMIAS
MAGNETIC MEASUREMENT OF HUMAN IRON STORES
HARVEY A ITANO, PhD
NIH Intramural Laboratories (NIAMD)
1953-1968
HEMOGLOBIN CHEMISTRY
JAMES H JANDL, MD
Harvard University School of Medicine
1956-1975
ERYTHROPOIETIC REGULATION
TRAINING GRANT IN HEMATOLOGY
CHARLES A JANEWAY, MD
Children’s Hospital, Harvard University
1951-1966
STUDIES ON BLOOD PROTEINS
AARON M JOSEPHSON, MD
Michael Reese Hospital, Chicago
1951-1966
SIGNIFICANCE OF ABNORMAL HEMOGLOBINS
IRVING M LONDON, MD
Albert Einstein College of Medicine
Massachusetts Institute of Technology
1956-1995
METABOLISM OF THE ERYTHROCYTE
REGULATION OF HEMOGLOBIN SYNTHESIS AND HEMATOPOIESIS
MAKIO MURAMAYAMA, PhD
NIH Intramural Laboratories (NIAMD, NIAMDD, NIDDK)
1955-1986
SICKLE CELL ANEMIA
ROSE G SCHNEIDER, MD
University of Texas, Galveston
1952-1981
HEMOGLOBIN VARIANTS IN RELATION TO DISEASE
N RAPHAEL SHULMAN, MD
NIH Intramural Laboratories (NIAMD, NIAMDD, NIDDK)
1955-1995
THROMBOCYTOPENIA, HEMOSTASIS, HEMOPHILIA
VIRAL HEPATITIS
FREDERICK STOHLMAN, Jr., MD
NIH Intramural Laboratories (NIAMD)
1953-1963
ERYTHROPOIESIS AND GRANULOPOIESIS
HEMATOPOIETIC STEM CELL BILOGY AND TRANSPLANTATION
SCOTT N SWISHER, MD
University of Rochester
Michigan State University
1951-1974
INTERACTIONS OF ANTIBODIES AND BLOOD CELLS
JOHN F TAYLOR, PhD
University of Louisville
1953-1975
SULFHYDRYL GROUPS AND PROPERTIES OF HEMOGLOBIN
1960s
RALPH O WALLERSTEIN, MD
Children’s Hospital, San Francisco
1957-1971
TISSUE IRON IN ANEMIA
TRAINING GRANT IN HEMATOLOGY
LOUIS R WASSERMAN, MD
Mt. Sinai Hospital, NY
1955-1968
LOCALIZATION AND KINETICS OF STORAGE IRON
ABNORMAL PROTEINS IN HEMATLOGIC DISORDERS
MAXWELL M WINTROBE, MD
University of Utah
1950-1972
HEREDITARY DISORDERS PROGRAM PROJECT
ROBERT I WEED, MD
University of Rochester
1957-1977
TRAINING GRANT IN HEMATOLOGY
ERYTHROCYTE ULTRASTRUCTURE AND METABOLISM
PROGRAM OF TRAINING FOR CLINICAL INVESTIGATION
G ADOLPH ACKERMAN, PhD
Ohio State University
1958-81
HEMOPOIESIS — HISTOCHEMICAL AND CYTOLOGICAL STUDIES
SURFACE DIFFERENTIATION OF DEVELOPING HEMIC CELLS
WILLIAM S BECK, MD
Massachusetts General Hospital, Harvard University
1960-1984
TRAINING GRANT IN HEMATOLOGY
RIBOSOMAL BINDING OF VITAMIN B12
HEMATOLOGIC ROLE OF VITAMIN B12 AND ITS ANALOGUES
C LOCKARD CONLEY, MD
Johns Hopkins University Hospital
1960-1980
TRAINING GRANT IN HEMATOLOGY
WILLIAM A EATON, MD, PhD
NIH Intramural Laboratories (NIAMD, NIAMDD, NIDDK)
1968-2011
SICKLE CELL HEMOGLOBIN KINETICS
PROTEIN FOLDING
SHIRLEY N EBBE, MD
St. Elizabeth’s Medical Center, Boston
Lawrence Berkeley Laboratory, University of California
1964-1987
KINETICS OF MEGAKARYOCYTE AND PLATELET TURNOVER
HEMOPOIETIC CELLULAR PROLIFERATION AND ITS REGULATION TRAINING
GRANT
GARY FELSENFELD, PhD
NIH Intramural Laboratories (NIAMD, NIAMDD, NIDDK)
1960-2011
GLOBIN GENE EXPRESSION
CHROMATIN STRUCTURE
ERNST R JAFFE, MD
Albert Einstein College of Medicine
1965-1983
METHEMOGLOBIN AND PYRIDINE NUCLEOTIDE METABOLISM
RESEARCH IN HEMATOLOGY TRAINING GRANT
RESEARCH AND HEREDITY CLINIC
RESEARCH IN RED BLOOD CELL DISEASES TRAINING GRANT
VICTOR D HERBERT, MD
Harvard University
Columbia University
SUNY Downstate,
Mt. Sinai School of Medicine
1961-1990
VITAMIN B12 AND FOLATE METABOLISM
RICHARD M LEVENSON, PhD
Duke University
1963-1985
IMMUNOLOGICAL STUDIES OF TISSUE ALLOANTIGENS
IMMUNOLOGICAL STUDIES OF PRIMATE MEMBRANE ANTIGENS
WARNER E LOVE, PhD
Johns Hopkins University
1959-1992
X-RAY STRUCTURE ANALYSIS OF BIOLOGICAL MOLECULES
X-RAY CRYSTAL STRUCTURE OF HB S AND OTHER MUTANT HB’S
ALAN N SCHECHTER, MD
NIH Intramural Laboratories (NIAMD, NIAMDD, NIDDK)
1965-2011
SICKLE CELL DISEASE
HEMOGLOBIN BIOCHEMISTRY
ROBERT F SCHILLING, MD
University of Wisconsin
1960-1975
PHYSIOLOGY OF VITAMIN B12 AND INTRINSIC FACTOR
TRAINING GRANT IN HEMATOLOGY
STANLEY L SCHRIER, MD
Stanford University
1960-2001
METABOLISM OF ERYTHROCYTE STROMA
TRAINING GRANT IN HEMATOLOGY
ROBERT S SCHWARTZ, MD
New England Medical Center Hospital, Tufts University
1963-1986
IMMUNOSUPPRESSION
STUDIES IN SYSTEMIC LUPUS ERYTHEMATOSUS
TRAINING PROGRAM IN CLINICAL IMMUNOLOGY
MONOCLONAL HUMAN LUPUS AUTOANTIBODIES
HYBRIDOMA-PRODUCED AUTOANTIBODIES — SYSTEMIC LUPUS
PAUL I TERASAKI, PhD
University of California, Los Angeles
1959-1995
HOMOTRANSPLANTABILITY BY HOST ALTERATION AND MATCHING
SEROLOGICAL TYPING FOR HOMOTRANSPLANTATION
HLA IN DISEASE AND TRANSPLANTATION
LEON P WEISS, MD
Johns Hopkins University
University of Pennsylvania
1961-1997
ELECTRON MICROSCOPY OF THE RETICULOENDOTHELIAL SYSTEM
EXPERIMENTAL HEMATOLOGY AND CELL BIOLOGY TRAINING GRANT
ROBERT C WOODWORTH, PhD
University of Vermont
1961-2000
NATURE OF IRON-BINDING PROTEINS
IRON DELIVERY VIA BLOOD; STRUCTURAL ROLE OF TRANSFERRIN
1970s
PHILIP AISEN, MD, PhD
Albert Einstein College of Medicine
1971-2006
IRON BINDING PROTEINS AND CONTROL OF IRON METABOLISM
IRON TRANSPORT IN MAMMALIAN CELLS
ROBERT H ALLEN, MD, PhD
Washington University
University of Colorado
1973-1994
THE STRUCTURE AND FUNCTION OF B12 BINDING PROTEINS
JOHN W ATHENS, MD
University of Utah
1975-1990
RESEARCH TRAINING IN HEMATOLOGY
ARTHUR BANK, MD
Columbia University
1965-2004
REGULATION OF HEMOGLOBIN SYNTHESIS
NORMAL/ABNORMAL CELL GROWTH
HEMATOLOGY TRAINING GRANT
REGULATION OF HUMAN GLOBIN GENE EXPRESSION
DOROTHY F BAINTON, MD, PhD
University of California, San Francisco
1969-1995
MATURATION AND FUNCTION OF BONE MARROW CELLS
EXPERIMENTAL AND CLINICAL STUDIES ON PMN LEUKOCYTES
MATURATION AND FUNCTION OF PMN LEUKOCYTES
EARNEST BEUTLER, MD, PhD
Scripps Research Institute
City of Hope National Medical Center
1971-2008
DIAGNOSIS AND THERAPY OF GAUCHER’S DISEASE
INVESTIGATIVE HEMATOLOGY TRAINING GRANT
GAUCHER DISEASE - MOLECULAR BIOLOGY & THERAPY
HEMOCHROMATOSIS — EPIDEMIOLOGY AND MOLECULAR MECHANISMS
DANE R BOGGS, MD
University of Pittsburg
1970-1988
KINETICS AND CONTROL OF NEUTROPHILIC GRANULOCYTES
H FRANKLIN BUNN, MD
Brigham & Womens Hospital, Harvard University
1975-2004
HEMOGLOBIN AIC IN PATIENTS WITH DIABETES MELLITUS
NONENZYMATIC GLUCOSYLATION OF PROTEIN IN DIABETES
REGULATION OF THE ERYTHROPOIETIN GENE
OXYGEN SENSING AND SIGNAL TRANSDUCTION
S WALTER ENGLANDER, PhD
University of Pennsylvania
1967-2000
PHYSICAL STUDIES OF BIOLOGICAL MACROMOLECULES
PROTEIN BONDING, STABILITY, AND FUNCTION
BERNARD G FORGET, MD
Boston Childrens Hospital, Harvard University
Yale University School of Medicine
1972-2007
HEMOGLOBIN MESSENGER RNA OF HUMAN ERYTHROID CELLS
MOLECULAR BIOLOGY OF HUMAN HEMOGLOBIN SYNTHESIS
MOLECULAR BIOLOGY OF THALASSEMIA
CELLULAR AND MOLECULAR ASPECTS OF HEMATOPOIESIS
PHYSICIAN SCIENTIST PROGRAM AWARD
HUMAN GLOBIN AND ERYTHROPOIETIN RECEPTOR GENE REGULATION
MOLECULAR GENETICS OF THE RED CELL MEMBRANE SKELETON
EUGENE GOLDWASSER, MD, PhD
University of Chicago
1974-1994
FORMATION OF ERYTHROPOIETIN IN CELL CULTURE
BIOCHEMICAL MECHANISM OF ERYTHROPOIETIN ACTION
HEMOPOIETIC STEM CELLS AND INDUCED DIFFERENTIATION
IRWIN J GOLDSTEIN, PhD
University of Michigan
1966-1981
PROTEIN-CARBOHYDRATE INTERACTION
DONALD WELDON JACOBSEN, PhD
Scripps Clinic and Research Foundation
Cleveland Clinic Foundation
1970-1991
MECHANISM OF B12 COENZYMES
B12 DEFICIENCY: COENZYME SYNTHESIS & INTERCONVERSION
B-12 BINDING PROTEINS: FUNCTION & CLINICAL SIGNIFICANCE
ENTEROHEPATIC CIRCULATION OF COBALAMINS
CHAN Y JUNG, MD, PhD
State University of New York at Buffalo
1969-2002
IDENTIFICATION AND ISOLATION OF SUGAR TRANSPORT CARRIER
VERNON M INGRAM, PhD, DSC
Massachusetts Institute of Technology
1970-1993
DIFFERENTIATION AND IMMUNOLOGY OF ERYTHROPOIESIS
HARVEY A ITANO, MD
University of California, San Diego
1971-1986
STUDIES IN MOLECULAR HEMATOLOGY
HARRY S JACOB, MD
University of Minnesota
1967-1982
ABNORMAL BLOOD CELL MEMBRANES IN DISEASE
YUET W KAN, MB, MD
University of California, San Francisco
1974-2009
STUDIES ON SICKLE CELL ANEMIA AND THALASSEMIA
ABNORMAL HEMOGLOBIN SYNTHESIS — MECHANISM & DETECTION
BASIC RESEARCH IN HEMATOLOGY TRAINING GRANT
CENTER OF EXCELLENCE IN MOLECULAR HEMATOLOGY
MURINE MODELS TO INVESTIGATE THE HEMATOLOGIC SYSTEM
HAIG H KAZAZIAN, MD
Johns Hopkins University
University of Pennsylvania
1970-1996
THE GENETIC CONTROL OF HEMOGLOBIN SYNTHESIS
SANFORD B KRANTZ, MD
Vanderbilt University
1972-2004
ERYTHROPOIETIN AND THE REGULATION OF ERYTHROPOIESIS
POSTGRADUATE TRAINING PROGRAM IN HEMATOLOGY
JUNE LASCELLES, PhD
University of California, Los Angeles
1966-1982
REGULATION OF HEME AND HEMOPROTEIN SYNTHESIS
DAVID G NATHAN, MD
Children’s Hospital Boston, Harvard University
1967-1981
RED CELL LYSIS IN DISEASE OF HEMOGLOBIN AND MEMBRANE
POSTGRADUATE TRAINING IN HEMATOLOGY
BIOCHEMICAL APPROACHES TO SICKLE CELL ANEMIA
CONSTANCE T NOGUCHI, PhD
NIH Intramural Laboratories (NIAMDD, NIDDK)
1975-2011
ERYTHROPOIESIS
ERYTHROPOIETIN RECEPTORS
JOHN C PARKER, MD
University of North Carolina
1968-1995
ION TRANSFER AND METABOLISM IN MAMMALIAN RED CELLS
RBC TRANSPORT AND METABOLISM
SERGIO S PIOMELLI, MD
New York University
Columbia University
1965-1991
THE MECHANISM OF RED CELL AGING - HEMOLYTIC ANEMIAS
PROTEIN SYNTHESIS IN ERYTHROID PRECURSORS
TRAINING GRANT FOR RESEARCH IN DISEASES OF BLOOD
GOETZ W RICHTER, MD
University of Rochester
1968-1991
IRON IN CELL PATHOLOGY
STEPHEN H ROBINSON, MD
Beth Israel Deaconess Medical Center, Harvard University
1968-1988
ORIGIN AND FATE OF BILE PIGMENTS
HEMATOLOGY CAREER TRAINING PROGRAM
FACTORS REGULATING HEMOPOIETIC CELL DIFFERENTIATION
HEMATOLOGY CAREER TRAINING PROGRAM
SHELDON P ROTHENBERG, MD
New York Medical College
State University of New York, Downstate
1963-1999
KINETICS OF B12, INTRINSIC FACTOR, AND OTHER PROTEINS
SPECIFIC RADIOASSAYS FOR FOLATE ANALOGUES
TRAINING PROGRAM IN HEMATOLOGY
JOHN R SACHS, MD
Yale University
State University of New York, Stony Brook
1970-2007
CATION TRANSPORT IN RED BLOOD CELLS
PHYSIOLOGICAL ASPECTS OF MEMBRANE CATION TRANSPORT
FUNCTIONAL STUDIES OF FULLY ACTIVE Na, K-ATPase
1980s
SAMUEL SCHWARTZ, MD
University of Minnesota
1964-1982
METABOLIC STUDIES OF CONGENITAL BOVINE PORPHYRIA
PORPHYRIN HEME AND BILE PIGMENT METABOLISM
DAVID SHEMIN, MD
Northwestern University
1968-1983
PORPHYRINS — ENZYMIC MECHANISMS AND CONTROL OF SYNTHESIS
PORPHYRIA — METABOLIC BASIS OF A NEUROLOGICAL DISORDER
STEPHEN B SHOHET, MD
University of California, San Francisco
1972-2002
MEMBRANE LIPID METABOLISM IN BLOOD CELLS
ARCHITECTURE OF ERYTHROCYTE SKELETON: BILAYER INTERFACE
RED CELL MEMBRANE STUDIES PROGRAM PROJECT
JERRY L SPIVAK, MD
Johns Hopkins University
1973-1995
ROLE OF ERYTHROPOIETIN IN TRANSCRIPTIONAL CONTROL
FUMITO C TAKETA, PhD
Medical College of Wisconsin
1971-1986
STRUCTURE AND FUNCTION OF HEMOGLOBIN
KOUICHI R TANAKA, MD
University of California, Los Angeles
1963-1992
METABOLIC AND BIOCHEMICAL STUDIES OF BLOOD CELLS
SHERMAN M WEISSMAN, MD
Yale University
1971-2014
HEMOGLOBIN mRNA IN THALASSEMIA — CLINICAL RESEARCH TRAINING
GRANT — GENETIC HEMATOLOGY TRAINING GRANT — MOLECULAR
MAPPING OF IMMUNE RESPONSE & COMPLEMENT GENES — MOLECULAR
HEMATOLOGY CENTER: GENE EXPRESSIONS AND GENOMIC ANALYSIS CORE
HOX CLUSTER INTERGENIC NON-CODING RNAs IN MYELOID
DIFFERENTIATION AND FUNCTION
ADEL A YUNIS, MD
University of Miami
1969-1988
CHLORAMPHENICOL-INDUCED MARROW APLASIA — PATHOGENESIS
BIOCHEMISTRY AND IMMUNOLOGY OF BLOOD DISEASES
GRADUATE TRAINING PROGRAM IN HEMATOLOGY
PATHOGENETIC MECHANISM IN BLOOD DISEASES PROGRAM PROJECT
INTERNAL MEDICINE — HEMATOLOGY TRAINING GRANT
DRUG-INDUCED BONE MARROW INJURY
JOHN W ADAMSON, MD
University of Washington
1976-92
IN VITRO STUDIES OF HEMATOPOIETIC REGULATION
ERYTHROPOIETIN: IN VITRO AND IN VIVO STUDIES IN MAN
STUDIES OF IN VITRO ERYTHROPOIETIC REGULATION
PATHOBIOLOGY OF BONE MARROW SUPPRESSION IN AIDS, ARC
JANE E BARKER, PhD
Jackson Laboratories
1980-2005
GENETIC ENGINEERING OF CELLS FROM ANEMIC ANIMALS
GENETIC ENGINEERING OF PLURIPOTENT STEM CELLS
IN UTERO STEM CELL TRANSFER FOR MPS VII
G VANN BENNETT, MD, PhD
Johns Hopkins University, Duke University
1981-2000
ERYTHROCYTE MEMBRANE CYTOSKELETON ASSOCIATIONS
INTERACTION OF ERYTHROCYTE MEMBRANE PROTEINS
RAYMOND J BERGERON, PhD
University of Florida
1982-2015
SYNTHESIS AND EVALUATION OF REDOX IRON CHELATORS
ORAL IRON CHELATORS PREDICATED ON DESFERRITHIOCIN
MARCEL E CONRAD, MD
University of South Alabama
1978-2002
IRON–INTESTINAL MUCOSAL METAL BINDING PROTEINS
REGULATORS OF IRON ABSORPTION
HARRY A DAILEY, PhD
University of Georgia
1981-2011
MEMBRANE BOUND ENZYMES OF THE HEME SYNTHETIC PATHWAY
TERMINAL ENZYMES OF THE HEME BIOSYNTHETIC PATHWAY
CHARACTERIZATION OF PROTOPORPHYRINOGEN OXIDASE
CHARACTERIZATION OF MAMMALIAN FERROCHELATASE
MAMMALIAN HEME SYNTHESIS
DAVID C DALE, MD
University of Washington
1976-2004
MARROW REGULATION IN CYCLIC HEMATOPOIESIS
CELLULAR AND GENETIC BASIS FOR CYCLIC HEMATOPOIESIS
ROBERT J DESNICK, PhD, MD
University of Minnesota
Mount Sinai School of Medicine
1974-2014
THERAPY OF METABOLIC DISEASES
STUDIES OF PORPHYRIA AND HUMAN HEME BIOSYNTHESIS
ALPHA-GALACTOSIDASES A & B — MOLECULE & CELL MECHANISMS
PORPHYRIA RARE DISEASES CLINICAL RESEARCH CONSORTIUM
GORDON D GINDER, MD
University of Iowa
University of Minnesota
Virginia Commonwealth University
1981-2011
GLOBIN GENE REGULATION DURING ERYTHROID DIFFERENTIATION
NORMAL AND PATHOLOGIC GENE EXPRESSION IN HEMATOPOIETIC CELLS
ROSS C HARDISON, PhD
Pennsylvania State University
1981-2014
ORGANIZATION AND EXPRESSION OF GLOBIN GENE LOCI
REGULATION AND EVOLUTION OF GLOBIN GENES
GLOBAL PREDICTIONS AND TESTS OF ERYTHROID REGULATION
DAVID E HARRISON, PhD
Jackson Laboratory
1974-2012
STEM CELL INTERACTIONS IN MARROW TRANSPLANTATION
EXPERIMENTAL HEMATOLOGY TRAINING GRANT
M P HEILBRUN, MD
University of Utah
1977-1995
PORPHYRIN BIOSYNTHESIS IN NORMAL AND DISEASE STATES
HEREDITARY HEMOCHROMATOSIS
JERRY KAPLAN, PhD
University of Utah
1982-2015
FACTORS REGULATING CELLULAR UPTAKE OF IRON
MOLECULAR REGULATION OF IRON AND HEME METABOLISM
GENETIC ANALYSIS OF MITOCHONDRIAL IRON METAB0LISM
MECHANISM AND REGULATION OF IRON EXPORT BY FERROPORTIN
KENNETH KAUSHANSKY, MD
University of Washington.
University of California, San Diego
1984-2014
ROLE OF COLONY-STIMULATION FACTORS IN HEMATOPOIESIS
STRUCTURE-FUNCTION ANALYSIS OF IL-3 AND ITS RECEPTOR
MOLECULAR AND CELLULAR BIOLOGY OF THROMBOPOIETIN
PHILIP A KNAUF, PhD
University of Rochester
1980-2007
ION TRANSPORT MECHANISMS IN BLOOD CELLS
SAMUEL E LUX, MD
Children’s Hospital Boston, Harvard University
1978-2006
PATHOPHYSIOLOGY OF RED CELL MEMBRANE DISEASES
HEMOLYTIC ANEMIAS OF PEROMYSCUS AND MUS
PROGRAM PHYSICAL SCIENTIST AWARD
MARK A MILANICK, PhD
Yale University
University of Missouri
1982-2009
ALTERATIONS IN THE NA PUMP STOICHIOMETRY
CYTOSOLIC MODULATION OF PLASMA MEMBRANE ION TRANSPORT
MECHANISM OF THE CA/H EXCHANGE PUMP
FROM CLINIC-BENCH & BACK CLINICAL BIODETECTIVE TRAINING
ICHIRO NAKAMURA, PhD
State University of New York at Buffalo
1982-2001
FACTORS CONTROLLING GRAFT-HOST INTERACTIONS
MOHANDAS NARLA, DSC
University of California, San Francisco
Lawrence Berkeley Laboratory
New York Blood Center
1980-2013
RED CELL DEFORMABILITY IN VITRO AND SURVIVAL IN VIVO
CLONING OF GENES FOR RED CELL MEMBRANE SKELETAL PROTEINS
PROGRAM PROJECT: RED CELL MEMBRANE STUDIES
PETER E NEWBURGER, MD
University of Massachusetts
1981-2014
STUDIES OF IN VITRO HEMATOPOIESIS
LEUKOCYTE GLUTATHIONE PEROXIDASE EXPRESSION
ID FAMILY REGULATION OF STEM CELL DEVELOPMENT
GENE EXPRESSION IN MATURE NEUTROPHILS
HOX CLUSTER INTERGEIC NON-CODING RNAs IN MYELOID
DIFFERENTIATION AND FUNCTION
1990s
PAUL R ORTIZ DE MONTELLANO, PhD
University of California, San Francisco
1982-2014
HEMOLYTIC ANEMIA AND ABNORMAL HEME CATABOLITES
HEMOPROTEIN OXIDATION AND HEME CATABOLISM
MAKIO OGAWA, MD, PhD
Medical University of South Carolina
1979-2010
HUMAN AND MURINE HEMOPOIESIS IN CULTURE
HEMOPOIETIC STEM CELLS
IN VITRO EXPANSION OF HEMATOPOIETIC STEM CELLS
IDENTIFICATION AND PURIFICATION OF HUMAN STEM CELLS
HEMATOPOIETIC ORIGIN OF MESENCHYMAL STEM CELLS
THALIA PAPAYANNOPOULOU, DSC, MD
University of Washington
1982-2003
STUDIES OF GLOBIN SWITCHING & ERYTHROID DIFFERENTIATION
FRANK W PUTNAM, MD, PhD
Indiana University
1976-1995
BLOOD PLASMA PROTEINS: STRUCTURE AND FUNCTION
PETER J QUESENBERRY, MD
University of Virginia
University of Massachusetts
Roger Williams Hospital
1980-2008
HEMOPOIETIC CELLULAR INTERACTIONS AND LITHIUM
HEMATOLOGY/ONCOLOGY TRAINING GRANT
HEMOLYMPHOPOIETIC GROWTH FACTORS PROGRAM PROJECT
REPETITIVE MARROW TRANSPLANTATION INTO NORMAL MICE
STEM CELL BIOLOGY PROGRAM PROJECT
STEM CELLS HOMING AND MOTILITY
MINIMAL TREATMENT MODELS OF STEM CELL ENGRAFTMENT
HEMATOPOIETIC CIRCADIAN RHYTHMS
GRIFFIN P RODGERS, MD
NIH Intramural Laboratories (NIDDK)
1984-2011
SICKLE CELL DISEASE
HEMOGLOBIN F
WENDELL F ROSSE, MD
Duke University
1982-1997
MEMBRANE ABNORMALITIES IN PNH
SHIGERU SASSA, MD, PhD
Rockefeller University
1983-2004
THE GENETICS AND DEVELOPMENT OF ERYTHROID HEME ENZYMES
HEME SYNTHESIS IN HUMAN LIVER CULTURE
ELIZABETH R SIMONS, PhD
Boston University School of Medicine
1982-2004
FUNCTIONAL STUDIES OF GRANULOCYTE MEMBRANES
ANTERO G SO, MD, PhD
University of Miami
1979-2002
FIDELITY OF DNA SYNTHESIS IN HEMATOPOIETIC TISSUES
GEORGE STAMATOYANNOPOULOS, MD, DSC
University of Washington
1982-2012
DEVELOPMENTAL BIOLOGY OF HEMOGLOBIN SWITCHING PROGRAM PROJECT
MOLECULAR MEDICINE TRAINING PROGRAM
MOLECULAR CONTROL OF HUMAN GLOBIN GENE SWITCHING
CENTER OF EXCELLENCE IN MOLECULAR HEMATOLOGY
MOLECULAR BIOLOGY OF HEMOPOIETIC STEM CELLS PROGRAM PROJECT
ELIZABETH C THEIL, PhD
North Carolina State University
Children’s Hospital of Oakland Research Institute
1971-2011
MECHANISM OF HEMOGLOBIN TRANSITION DURING DEVELOPMENT
RED CELL FERRITIN MRNA AND PROTEIN — STRUCTURE/FUNCTION
IRON & OXYGEN BIOLOGY IN SCH, HH & BETA-THAL MICE
FERRITIN: PROTEIN/mRNA/DNA IN FE AND OXYGEN REGULATION/METABOLISM
DOROTHEA ZUCKER-FRANKLIN, MD
New York University School of Medicine
1968-1993
ULTRASTRUCTURE OF LEUKOCYTES AND PLATELETS
M AMIN ARNAOUT, MD
Massachusetts General Hospital, Harvard University
1989-2014
MOLECULAR BASIS OF MO1/LFA-L DEFICIENCY
GRANULOCYTE CYTOPLASMIC ANTIGENS IN RENAL VASCULITIS
PHAGOCYTE MEMBRANE
STRUCTURE AND FUNCTION OF BETA2 INTEGRIN
ROLE OF THE ZINC FINGER TRANSCRIPTION FACTOR ZBP89 IN BLOOD AND
VASCULAR DEVELOPMENT
NANCY BERLINER, MD
Yale University
1991-2003
CONTROL OF TRANSCOBALAMIN I, NEUTROPHIL GRANULE PROTEIN
MOLECULAR CONTROL OF NEUTROPHIL-SPECIFIC GENE EXPRESSION
CDP/CUT AND MYELOID DIFFERENTIATION
JAMES J BIEKER, PhD
Mount Sinai School of Medicine
1993-2013
FUNCTION OF A PUTATIVE DETERMINANT IN HEMATOPOIESIS
BIPOTENTIAL LINEAGE DETERMINATION BY EKLF
REDIRECTING HEMOGLOBIN EXPRESSION DURING HUMAN ES CELL DIFFERENTIATION
HEMATOPOIETIC STEM CELL COMMITMENT — MOLECULAR REGULATION
HAL E BROXMEYER, PhD
Indiana University
1985-2015
REGULATION OF HEMATOPOITIC CELL PRODUCTION TRAINING GRANT
CHEMOKINES/CYTOKINES AND RECEPTORS IN STEM CELL HOMING
REGULATING HEMATOPOIETIC STEM CELLS AND HEMATOPOIESIS
FOR CLINICAL EFFICACY
JANE-JANE CHEN, PhD
Massachusetts Institute of Technology
1994-2013
REGULATION OF PROTEIN SYNTHESIS AND ERYTHROPOIESIS
STRUCTURE/FUNCTION OF HEME REGULATED ELF-2ALPHA KINASE
HRI/elF2aP SIGNALING PATHWAY AS POTENTIAL PHARMACEUTICAL
TARGETS FOR THALASSEMIA
JOHN L CLEVELAND, PhD
St. Jude Childrens Research Hospital
Scripps Florida Research Institute
1991-2010
C-MYC FUNCTION IN MYELOID CELL GROWTH & DIFFERENTIATION
C-MYC ROLE IN HEMATOPOIESIS, VASCULOGENESIS, AND ANGIOGENEISIS
ALAN D D’ANDREA, MD
Dana Farber Cancer Institute, Harvard University
1992-2011
STRUCTURE AND FUNCTION OF THE ERYTHROPOIETIN RECEPTOR
ABNORMAL SIGNAL TRANSDUCTION IN HEMATOPOIETIC DISEASE
REGULATION OF THE FANCONI ANEMIA PATHWAY BY UBIQUITINATION
CAROLINE ENNS, PhD
Oregon Health and Science University
1989-2015
STRUCTURE - FUNCTION OF THE HUMAN TRANSFERRIN RECEPTOR
FUNCTION OF THE HEMOCHROMATOSIS PROTEIN
FUNCTIONAL DOMAINS OF THE TRANSFERRIN RECEPTOR
REGULATION AND FUNCTION OF TRANSFERRIN RECEPTOR-2
MARK T GROUDINE, MD, PhD
University of Washington
1992-2011
FUNCTION OF HUMAN & MOUSE B GLOBIN LOCUS CONTROL REGIONS
JAMES P KUSHNER, MD
University of Utah
1994-2013
RESEARCH TRAINING GRANT IN HEMATOLOGY
HEREDITARY HEMOCHROMATOSIS
CENTER OF EXCELLENCE IN MOLECULAR HEMATOLOGY
PORPHYRIN BIOSYNTHESIS IN NORMAL AND DISEASE STATES
HEMOCHROMATOSIS MODIFIER GENES
JAMES N IHLE, PhD
St. Jude Children’s Hospital
1990-2008
CYTOKINE REGULATED GROWTH OF HEMATOPOIETIC CELLS
IHOR R LEMISCHKA, PhD
Princeton University
Mount Sinai School of Medicine
1990-2010
MOLECULAR STUDIES OF HEMATOPOIETIC STEM CELLS
CHARACTERIZATION OF HUMAN HEMATOPOIETIC STEM CELLS
ANALYSES OF STEM CELL PLASTICITY
GLOBAL GENOMIC ANALYSIS OF HUMAN HEMATOPOIESIS
TIMOTHY J LEY, MD
Washington University
1987-2010
REGULATION OF FETAL AND ADULT HUMAN HEMOGLOBIN PRODUCTION
GRANZYMES AND CYTOTOXIC LYMPHOCYTE FUNCTIONS
BING LIM, MD, PhD
Beth Israel Deaconess Medical Center, Harvard University
1991-2009
HEMATOPOIETIC DIFFERENTIATION IN EMBRYONAL STEM CELLS
HEMATOPOIETIC SPECIFIC GENES IN STEM CELL DEVELOPMENT
LYSOSOMAL PROTEOLYSIS IN HEMATOPOIETIC CELLS
BARBARA A MILLER, MD
Pennsylvania State University, Hershey Medical Center
1994-2012
SIGNAL TRANSDUCTION MECHANISMS OF ERYTHROPOIETIN
2000s
JEFFERY L MILLER, MD
NIH Intramural Laboratories (NIDDK)
1995-2011
ERYTHROID CELL GENOMICS
ONTOGENY OF GLOBIN GENE EXPRESSION
IRON METABOLISM
KENNETH N RAYMOND, PhD
University of California, Berkeley
1983-2010
FERRIC ION SEQUESTERING AGENTS: IRON REMOVAL IN MAN
THERAPEUTIC MULTIDENTATE IRON SEQUESTERING AGENTS
CHRISTA E MULLER-SIEBURG, PhD
Burnham Institute for Medical Research
1989-2013
ISOLATION OF HEMATOPOIETIC AND STROMAL CELL PRECURSORS
GENE TRANSFER INTO STEM CELLS VIA STROMAL CELL PRODUCERS
STROMAL CELL MOLECULES REGULATE STEM CELL PROLIFERATION
EPIGENETIC CONTROL OF HEMATOPOIETIC STEM CELLS
STEPHEN DAVID NIMER, MD
University of California, Los Angeles
Memorial-Sloan Kettering Cancer Center
1990-2012
CELLULAR CONTROL OF HEMOPOIETIC GROWTH FACTOR PRODUCTION
FUNCTION OF MEF IN HEMATOPOIETIC CELLS
MOLECULAR PATHOGENESIS OF MYELOID LEUKEMIA
VITAMIN D3 INDUCIBLE GENES MEDIATING DIFFERENTIATION
STUART H ORKIN, MD
Children’s Hospital Boston, Harvard University
1993-2015
MOLECULAR DEVELOPMENTAL HEMATOPOIESIS
CENTER FOR MOLECULAR DEVELOPMENTAL HEMATOPOIESIS
WILLIAM R OSBORNE, PhD
University of Washington
1989-2008
PURINE NUCLEOSIDE PHOSPHORYLASE GENE TRANSFER
CANINE G-CSF GENE TRANSFER
CLINICAL MODEL OF ERYTHROPOIETIN GENE THERAPY
ENCAPSULATED CELLS TO TREAT TYPE-1 DIABETES
MICHAEL K PANGBURN, PhD
University of Texas
1984-2012
REGULATION OF COMPLEMENT BY MEMBRANE PROTEINS
ACTIVATION OF THE ALTERNATIVE PATHWAY OF COMPLEMENT
STEPHEN T SMALE, PhD
University of California, Los Angeles
1991-2016
REGULATION OF TDT EXPRESSION DURING LYMPHOPOIESIS
BIOLOGICAL FUNCTIONS AND MECHANISMS OF ACTION OF IKAROS PROTEINS
DANIEL G TENEN, MD
Beth Israel Deaconess Medical Center, Harvard University
1994-2013
REGULATION OF THE HUMAN CD34 STEM CELL GENE
HEMATOPOIETIC STEM CELL COMMITMENT
FRANK M TORTI, MPH, MD
Stanford University
Wake Forest University
1989-2012
TUMOR NECROSIS FACTOR AND IRON METABOLISM
FERRITIN, IRON HOMEOSTASIS, AND CELLULAR STRESS
DAVID A. WILLIAMS, MD
Indiana University
Cincinnati Children’s Hospital
Children’s Hospital Boston
1994-2011
STEEL GENE PRODUCT AND STEM CELL PROLIFERATION
GENETIC MODIFICATION — ALTERNATIVE SOURCES OF STEM CELLS
CORE CENTERS OF EXCELLENCE IN MOLECULAR HEMATOLOGY
RAC PROTEIN IN HEMATOPOIETIC CELL SURVIVAL AND FUNCTION
CHEMORESISTANCE AND STEM CELL SELECTION
DEVELOPMENT OF A PEDIATRIC MYELODYSPLASTIC
SYNDROME PATIENT REGISTRY
NOVEL THERAPIES FROR FANCONI ANEMIA
NANCY CATHERINE ANDREWS, PhD, MD
Boston Childrens Hospital, Harvard University
Duke University
1998-2013
REGULATION OF IRON HOMEOSTASIS
IRON TRANSPORT AND ERYTHROPOIESIS
MODIFIERS OF IRON LOADING IN MICE
GERD A BLOBEL, MD, PhD
Children’s Hospital of Philadelphia, University of Pennsylvania
1999-2014
TRANSCRIPTIONAL ERYTHROID CELL DIFFERENTIATION
MECHANISMS OF GENE REPRESSION DURING HEMATOPOIETIC DIFFERENTIATION
CHROMATIN LOOPS AT THE BETA GLOBIN LOCUS
EMERY H BRESNICK, PhD
University of Wisconsin
1996-2015
MECHANISM OF THE HUMAN BETA GLOBIN LOCUS CONTROL REGION
COACTIVATORS THAT MEDIATE BETA GLOBIN LCR FUNCTION
TRANSCRIPTIONAL CONTROL OF HEMOGLOBIN SYNTHESIS
HEMATOPOIETIC REGULATION OF GATA SWITCHES
NOVEL ERYTHROID MEMBRANE PROTEIN
JORG BUNGERT, PhD
Northwestern University
University of Florida
1997-2014
STRUCTURE/FUNCTION OF THE HUMAN B-GLOBIN LCR
LOCUS CONTROL REGION FUNCTION ON INACTIVE X-CHROMASOMES
FUNCTIONAL PROTEOMICS IN DIFFERENTIATING ERYTHROID CELLS
ANDREW B DANCIS, MD
University of Pennsylvania
1998-2013
IRON TRAFFICKING IN SACCHAROMYCES CEREVISIAE
BIOCHEMISTRY AND GENETICS OF IRON TRANSPORT IN MITOCHONDRIA
SHUO LIN, PhD
Medical College of Georgia
University of California, Los Angeles
1998-2015
GENETIC ANALYSIS OF HEMATOPOIETIC DEVELOPMENT
TARGETED MUTAGENESIS IN ZEBRAFISH BY ANIMAL CLONING
ZEBRAFISH CORE – UCLA MOLECULAR HEMATOLOGY CENTER OF
EXCELLENCE
LEONARD I ZON, MD, PhD
Children’s Hospital Boston, Harvard University
1996-2013
INDUCTION OF HEMATOPOIETIC STEM CELLS DURING ZEBRAFISH
EMBRYOGENESIS — COMPARATIVE APPROACH TO GLOBIN REGULATION/
THALASSEMIA — CHARACTERIZING THE ZEBRAFISH GENOME
COMPARATIVE APPROACH TO THE HEMATOPOIETIC STEM CELL
