Contact Details

Barbara Rehermann, MD
Chief, Immunology Section
Liver Diseases Branch
NIDDK, NIH
10 Center Drive
Bldg. 10, Room 9B16
Bethesda, MD 208927

Ph: 301-402-7144
Fax: 301-402-0491
Rehermann@nih.gov

Immunology Section Images

Barbara Rehermann, M.D. Lab Members
Current Projects Lab Alumni
Recent Publications  


Intracellular innate immune response to hepatitis C virus
Intracellular innate immune response to hepatitis C virus. Hepatocytes sense double-stranded RNA (dsRNA) via the cytoplasmic pattern recognition receptor RIG-I and the endosomal pattern recognition receptor TLR3. Secreted IFN-b induces an antiviral state in neighboring uninfected cells via JAK/STAT-mediated signaling. HCV interferes with this pathway at multiple points (for a review see J Clin Invest 119:1745-54).



Adaptive immune responses to HCV and viral escape
Adaptive immune responses to HCV and viral escape (for a review see Nature Reviews Immunology 2005; 5: 215-2)


Page last updated: January 20, 2012

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