Funding for Special   Communities

Intrauterine Environment

The Intrauterine Environment Program supports both basic and clinical research investigating the mechanisms by which the intrauterine environment alters metabolic responses in the offspring. A particular focus will be the role of maternal diet on the development of obesity and the pathophysiological consequences of obesity, particularly Type 2 diabetes, on the offspring. Investigations will be aimed at elucidating the signals that mediate the long term effects of prenatal environment on the offspring including, but not limited to:

  1. intracellular signaling pathways,
  2. inflammatory cytokines,
  3. nutrient sensing pathways, and
  4. epigenetic imprinting.

These pathways will be studied in a number of target tissues including liver, adipose, skeletal muscle, pancreas and brain. Clinical studies which expand on basic research findings and/or explore basic mechanisms involved in human obesity are encouraged. The long term goal of this program is to identify molecular targets that could be therapeutically altered in order to prevent or alleviate the increasing incidence of obesity and Type 2 diabetes.

For additional information, contact Dr. Corinne Silva, Director, Intrauterine Environment Program.

NIH Divison of Nutrition Research Coordination (DNRC)

DNRC coordinates nutrition research and research training across The NIH and the Federal Government, and maintains the Human Nutrition Research Information Management database, the Nutrition Calendar and education materials.

Resources for Researchers

Clinical Research

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See Also

Committees and Advisory Groups

Funding Opportunities

Conferences

Related Reports

NIDDK Staff

  • Dr. Mary Evans,
    Director, Special Projects in Nutrition, Obesity, and Digestive Diseases
  • Dr. Jay Everhart, Director of the Epidemiology and Data Systems Branch
  • Dr. Frank Hamilton, Gastrointestinal Mucosa and Immunology Program Director.
  • Dr. Stephen James, Director, Division of Digestive Diseases and Nutrition
  • Dr. Robert Karp, Director of the Genetics and Genomics Programs in Digestive Diseases and Nutrition
  • Dr. Michael May, Director, Gastrointestinal Neuroendocrinology Program
  • Dr.Carolyn Miles, Director; Clinical Obesity and Nutrition Program
  • Dr. Judith Podskalny, Director, Research Fellowship & Career Development Program and Digestive Disease Centers Program
  • Dr. Patricia Robuck, Program Director for Clinical Trials in Digestive Diseases and Nutrition
  • Dr. Corinne Silva, Director, Intracellular and Intrauterine Signaling Programs

Page last updated: July 26, 2011

General inquiries may be addressed to:
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