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L: Cyst of B. mandrillaris. R: Trophozoite of B. mandrillaris in culture. Both images under high magnification.

Balamuthia mandrillaris is a free-living ameba (a single-celled living organism) naturally found in the environment. Balamuthia can cause a very rare but serious infection of the brain and spinal cord called Granulomatous Amebic Encephalitis (GAE).

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