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News Releases About NIGMS-Supported Research

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News Releases from NIGMS

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February 2013
Genomic Responses in Mice Poorly Mimic Human Inflammatory Diseases Link to external Web site
February 11, 2013 • Massachusetts General Hospital

Canine Genetics May Hold Clues to Human Skull Development Link to external Web site
February 8, 2013 • National Institutes of Health

Peptide Could Treat Cancers, Neurological Disorders and Infectious Diseases Link to external Web site
February 7, 2013 • University of Texas Southwestern Medical Center

For Drug Makers, New 3-D Control Opens Wealth of Options Link to external Web site
February 7, 2013 • Yale University

Excess Protein Linked to Development of Parkinson's Disease Link to external Web site
February 7, 2013 • University of California, San Diego

Computational Modeling Reveals Growing Economic Burden of Chagas Disease Link to external Web site
February 7, 2013 • Sabin Vaccine Institute

Protein Protects Chromosome Ends Using Two-Step Process Link to external Web site
February 6, 2013 • Scripps Research Institute

Tiny Weed Reveals Unexpected Connection Between Hormone Pathways Link to external Web site
February 5, 2013 • Salk Institute for Biological Studies

Biologists Map Deleterious Interaction Between Nuclear, Mitochondrial Genes Link to external Web site
February 5, 2013 • Indiana University

 
January 2013
Tilt of a Cell-Surface Receptor Key to Preventing Cancer Link to external Web site
January 31, 2013 • Ludwig Institute for Cancer Research

How Two “Master Regulators” Help Split Chromosomes Evenly When Cells Divide Link to external Web site
January 31, 2013 • Oklahoma Medical Research Foundation

Researchers Unveil First Artificial Enzyme Created by Evolution in a Test Tube Link to external Web site
January 30, 2013 • University of Minnesota

“Super” Enzyme Protects Against Dangers of Oxygen Link to external Web site
January 29, 2013 • Johns Hopkins Bloomberg School of Public Health

New Tool for Mining Bacterial Genome for Novel Drugs Link to external Web site
January 25, 2013 • Vanderbilt University

iPS Cell Derived Tissues Not Rejected When Transplanted Into Mice Link to external Web site
January 25, 2013 • Boston University Medical Center

Study Sheds Light on Gene’s Role in Rheumatoid Arthritis Link to external Web site
January 24, 2013 • University of Michigan

Neuroinflammation May Be Behind General-Anesthesia-Associated Learning Disabilities Link to external Web site
January 24, 2013 • Massachusetts General Hospital

Blocking Digestive Enzymes May Reverse Shock, Stop Multiorgan Failure Link to external Web site
January 23, 2013 • University of California, San Diego

Unusual Biochemistry Yields Lethal Bacterial Protein Link to external Web site
January 22, 2013 • University of Illinois

Protein Reins in Pathway Linked to Immune Diseases Link to external Web site
January 22, 2013 • The University of Texas MD Anderson Cancer Center

DNA Repair Mechanism Suggests New Approach for Targeting HIV Link to external Web site
January 21, 2013 • Johns Hopkins University School of Medicine

Study Reveals Promising Molecular Target for Treating Parkinson’s Link to external Web site
January 18, 2013 • University of Pennsylvania School of Veterinary Medicine

Novel Technique Reveals Dynamics of Telomere DNA Structure Link to external Web site
January 17, 2013 • University of California, Santa Cruz

Molecular Twist Helps Maintain Balance of Histones to DNA Link to external Web site
January 17, 2013 • University of North Carolina Health Care

Lack of Key Enzyme in Folic Acid Metabolism Leads to Birth Defects in Mice Link to external Web site
January 17, 2013 • University of Texas at Austin

Critical Transcription Factor Co-Exists in Two Distinct States Link to external Web site
January 17, 2013 • Lawrence Berkeley National Laboratory

Computational Approach Reveals Clues to Why Proteins Misfold Link to external Web site
January 14, 2013 • Rice University

Clathrin’s Molecular “Switch” May Play Role in Tumor Suppression Link to external Web site
January 14, 2013 • Indiana University

“Quality Control” Protein Found to Have Unusually Flexible Structure Link to external Web site
January 14, 2013 • Scripps Research Institute

Virus Caught in the Act of Infecting a Cell Link to external Web site
January 11, 2013 • University of Texas at Austin

Repressing Single Protein Prompts Fibroblasts to Become Neurons Link to external Web site
January 10, 2013 • University of California, San Diego

Multiple Sclerosis Drug May One Day Treat Colorectal Cancer Link to external Web site
January 9, 2013 • Virginia Commonwealth University

New Compound Overcomes Drug-Resistant Staph Infection in Mice Link to external Web site
January 7, 2013 • University of Illinois

Structure Helps Define Protein’s Role in Cell-Cell Interactions Link to external Web site
January 6, 2013 • Scripps Research Institute

Waste Removal in Worms Reveals Insights Into Calcium Signaling Link to external Web site
January 4, 2013 • University of Rochester Medical Center

Computational Modeling Suggests Changes in Cellular Metabolism Trigger Diabetes Link to external Web site
January 4, 2013 • University of California, Santa Barbara

Rare Form of Active “Jumping Genes” Found in Mammals Link to external Web site
January 3, 2013 • Johns Hopkins Medicine

Interactions Between Chromatin and Genetic Factors Influence Gene Activities Link to external Web site
January 3, 2013 • University of California, San Diego

Scientists Uncover Itch-Specific Nerve Cells in Skin Link to external Web site
January 2, 2013 • Johns Hopkins Medicine

 
December 2012
New Clues on How Hepatitis C Virus Hijacks Cell’s Protein-Making Machinery Link to external Web site
December 27, 2012 • University of Colorado School of Medicine

Researchers Developing New Class of Malaria Drugs by Modeling Natural Inhibitor Link to external Web site
December 26, 2012 • University of Pennsylvania

Detailed Molecular Structure Reveals Inner Workings of Chinese Herbal Medicine Link to external Web site
December 23, 2012 • Scripps Research Institute

Study Uncovers Molecular Basis of Resetting the Body’s “Food Clock” Link to external Web site
December 21, 2012 • University of California, San Francisco

New Approach to Destroy Disease-Associated RNAs in Cells Link to external Web site
December 20, 2012 • Scripps Research Institute

Chromosome “Anchors” Organize DNA During Cell Division Link to external Web site
December 20, 2012 • Salk Institute for Biological Studies

Cholesterol Helps Regulate Key Signaling Proteins in the Cell Link to external Web site
December 19, 2012 • University of Illinois at Chicago

Molecular Networks Form Basis of New Computational Model of the Cell Link to external Web site
December 16, 2012 • University of California, San Diego

Study Uncovers New Drug Targets for Aggressive Brain Tumor Link to external Web site
December 14, 2012 • University of Pittsburgh Schools of the Health Sciences

Molecular “Snapshots” Map Out Production of Cellulose in Bacteria Link to external Web site
December 13, 2012 • University of Virginia

Tagging Protein for Destruction Bolsters Some of Its Functions Link to external Web site
December 12, 2012 • Michigan State University

Major Shift in Human Intestinal Bacterial Populations in Past 100 Years Link to external Web site
December 12, 2012 • University of Oklahoma

Anti-Aging Gene Identified as Tumor Suppressor in Mice Link to external Web site
December 11, 2012 • University of Michigan

Porcupine Quill Structure Provides Model for Future Medical Devices Link to external Web site
December 10, 2012 • Brigham and Women's Hospital

Gene Network Illuminates Stress, Mutation and Adaptation Responses in Bacteria Link to external Web site
December 6, 2012 • Baylor College of Medicine

Different Genes Behind Same Adaptation to Thin Air Link to external Web site
December 6, 2012 • Case Western Reserve University

Biochemists Trap a Chaperone Machine in Action Link to external Web site
December 6, 2012 • University of Massachusetts at Amherst

Multitasking Plasmonic Nanobubbles Kill Some Cells, Modify Others Link to external Web site
December 3, 2012 • Rice University

Key Hormone Plays Role in Shaping Plant Organs Link to external Web site
December 3, 2012 • Carnegie Institution for Science

How Two Proteins Help Form Cells’ Autophagosomes Link to external Web site
December 2, 2012 • Scripps Research Institute

 
November 2012
Native Americans and Northern Europeans More Closely Related Than Previously Thought Link to external Web site
November 30, 2012 • Genetics Society of America

Specific Region of Notch Protein Key to Discriminating Between Ligands Link to external Web site
November 29, 2012 • Baylor College of Medicine

Rules Devised for Building Proteins Not Found in Nature Link to external Web site
November 29, 2012 • University of Washington

Roadmap of Mitochondrial Protein Acetylation Offers New Clues to Aging, Disease Link to external Web site
November 29, 2012 • University of Wisconsin, Madison

Iron Crucial for Growth of Pathogenic Bacteria Link to external Web site
November 29, 2012 • Kansas State University

Binding Partners Activate Chromatin Remodeling Protein by Triggering Shape Change Link to external Web site
November 29, 2012 • Stowers Institute for Medical Research

New Chemical Toolkit Simplifies Creation of Drug Compounds Link to external Web site
November 28, 2012 • The Scripps Research Institute

New Mechanism for Cancer Progression Discovered Link to external Web site
November 27, 2012 • UNC Lineberger Comprehensive Cancer Center

Component of the Immune Response Points to Potential New Cancer Therapies Link to external Web site
November 27, 2012 • The Scripps Research Institute

Weather Forecast Techniques Used to Predict Flu Outbreaks Link to external Web site
November 26, 2012 • Columbia University Mailman School of Public Health

Study Uncovers What Keeps a Cell's Energy Source Going Link to external Web site
November 26, 2012 • Perelman School of Medicine, University of Pennsylvania

Metabolic Protein Launches Sugar Feast That Nurtures Brain Tumors Link to external Web site
November 26, 2012 • The University of Texas MD Anderson Cancer Center

Inactivation of Specific DNA Sites Governs X Chromosome Inactivation Link to external Web site
November 26, 2012 • UNC Lineberger Comprehensive Cancer Center

Calcium “Accelerator” Helps Keep Cell Power Supply Going Link to external Web site
November 25, 2012 • Temple University Health System

Structural Studies Provide New Insights on How Flu Replicates Link to external Web site
November 22, 2012 • Scripps Research Institute

DNA Methylation Profiles Offer New Measure of “Biological” Age Link to external Web site
November 21, 2012 • University of California, San Diego

Breakthrough in Determining Cause of Disabling Sleep Disorder Link to external Web site
November 21, 2012 • Emory University

Certain Mutated Cells Ignore Signs to Stop DNA Replication—With Disastrous Results Link to external Web site
November 19, 2012 • University of Southern California

Study Reveals How DNA Packaging Complex is Regulated Link to external Web site
November 16, 2012 • University of Utah Health Sciences

Study Tracks Genetic Underpinnings of Aggressive Behavior Link to external Web site
November 15, 2012 • University of Illinois at Urbana-Champaign

Scientists Develop Single-Cell Imaging to Watch the Cell Clock Link to external Web site
November 13, 2012 • Ohio State University

New Type of Bacterial Protection Found Within Cells Link to external Web site
November 13, 2012 • University of California, Irvine

Cooperative Members of Yeast Population Have Survival Advantage Link to external Web site
November 13, 2012 • Massachusetts Institute of Technology

Safety Gear Reduces Risk of Head Injuries in Skiing and Snowboarding Link to external Web site
November 12, 2012 • Johns Hopkins Medicine

Yeast "Mothers" Sacrifice for Their Offspring Link to external Web site
November 8, 2012 • University of Califormia, San Francisco

New Player in Asymmetric Cell Division Uncovered Link to external Web site
November 8, 2012 • University of Massachusetts at Amherst

Extra Chromosome 21 Removed From Down Syndrome Cell Line Link to external Web site
November 8, 2012 • University of Washington

Transcription Factor Found to Play Role in Repairing Damaged DNA Link to external Web site
November 1, 2012 • University at Buffalo, The State University of New York

Gene Required for Nerve Regeneration Identified Link to external Web site
November 1, 2012 • Penn State

Computers "Taught" to ID Regulating Gene Sequences Link to external Web site
November 1, 2012 • Johns Hopkins Medicine

Compound Shows Therapeutic Promise in Mouse Model of Huntington's Disease Link to external Web site
November 1, 2012 • Lawrence Berkeley National Laboratory

Bacteria Yield Clues About Protein Aggregation in ALS and Alzheimer's Link to external Web site
November 1, 2012 • Yale University

 
October 2012
New Type of Quick-Release Medical Tape Minimizes Neonatal Skin Injury Link to external Web site
October 29, 2012 • Brigham and Women's Hospital

Scientists Block Toxic Protein That Plays Key Role in Lou Gehrig's Disease Link to external Web site
October 28, 2012 • Gladstone Institutes

Study Zeroes in on How Stem Cells Maintain Undifferentiated State Link to external Web site
October 26, 2012 • Carnegie Institution

Mung Bean Extract Helps Protect Against Sepsis in Mice Link to external Web site
October 26, 2012 • The Feinstein Institute for Medical Research

Researchers Uncover New Target for Anticancer Drug Development Link to external Web site
October 25, 2012 • University of Colorado at Boulder

Protein Serves as Gatekeeper for Maintaining Health of Cell's Energy Source Link to external Web site
October 25, 2012 • University of Pennsylvania School of Medicine

Harmful Genes Are Widespread in Yeast But Hold Hidden Benefits Link to external Web site
October 25, 2012 • University of Michigan

Far From Random, Evolution Follows a Predictable Genetic Pattern Link to external Web site
October 25, 2012 • Princeton University

Anesthesia Drugs Really Do Put Us to Sleep Link to external Web site
October 25, 2012 • University of Pennsylvania

Study Suggests Bacteria Sparked Evolution of Multicellular Life Link to external Web site
October 24, 2012 • University of California, Berkeley

Lactation Protein Suppresses Tumors and Metastasis in Breast Cancer Link to external Web site
October 23, 2012 • University at Buffalo, The State University of New York

Structure of an Unmodified G-Protein-Coupled Receptor in Its Natural Habitat Link to external Web site
October 22, 2012 • University of California, San Diego

Protein-Labeling Technique Allows Visualization of Molecules Inside Cells Link to external Web site
October 21, 2012 • Massachusetts Institute of Technology

Evolution of New Genes Captured Link to external Web site
October 19, 2012 • University of California, Davis

Researchers Unveil Structure of 'Molecular Machine' That Initiates DNA Transcription Link to external Web site
October 18, 2012 • Rutgers University

Lipid Droplets Play an Unexpected Role in Embryo Development Link to external Web site
October 18, 2012 • University of Rochester

Computer Modeling Feat Sheds Light on Protein Channel's Function Link to external Web site
October 18, 2012 • California Institute of Technology

Bacterial Biofilms Provide Insight Into How to Engineer Organs Link to external Web site
October 18, 2012 • University of Texas at Dallas

Cold Viruses Point the Way to New Cancer Therapies Link to external Web site
October 16, 2012 • Salk Institute for Biological Studies

Mice at Risk of Asthma, Allergies Can Fight Off Skin Cancer Link to external Web site
October 15, 2012 • Washington University in St. Louis

Shape Matters in DNA Nanoparticle Therapy Link to external Web site
October 12, 2012 • Northwestern University

NIGMS Awards $1.6 Million for the Development of Methods to Make Complex Natural Products Link to external Web site
October 12, 2012 • The Scripps Research Institute

Using Cell Phone Data to Curb the Spread of Malaria Link to external Web site
October 11, 2012 • Harvard School of Public Health

New National Centers for Systems Biology to Study Microbial Communities and RNA
October 11, 2012 • National Institute of General Medical Sciences

New Insights on Quorum Sensing Suggest Infection Control Strategy Link to external Web site
October 11, 2012 • University of Washington

Multicolored Probes That Reveal Bacterial Growth Offer Powerful New Tool Link to external Web site
October 11, 2012 • Indiana University

Fruit Flies Reveal Forces That Shape Genetic Variation Link to external Web site
October 11, 2012 • University of California, Davis

NIGMS Grantee Honored with Nobel Prize in Chemistry
October 10, 2012 • National Institute of General Medical Sciences

"Molecular Sled" Carries Viral Enzyme Along DNA to Find Targets Link to external Web site
October 10, 2012 • Brookhaven National Laboratory

New Screening Method to Aid RNA Drug Development Research Link to external Web site
October 9, 2012 • The Scripps Research Institute

Infections Are Better Prevented When Hospitals Cooperate Link to external Web site
October 9, 2012 • University of Pittsburgh Schools of the Health Sciences

Putting a Block on Neuropathic Pain Before It Starts Link to external Web site
October 8, 2012 • Boston Children's Hospital

Award Enables Systematic Study of Protein Linked to Hereditary Spastic Paraplegia Link to external Web site
October 8, 2012 • Rice University

Electrical Activity in Clock Neurons Helps Control Circadian Rhythms Link to external Web site
October 4, 2012 • New York University

Novel Technology Identifies Biomarkers for Ulcerative Colitis Link to external Web site
October 3, 2012 • The Scripps Research Institute

'Humanized' Mice Advance Study of Rheumatoid Arthritis Link to external Web site
October 3, 2012 • Northwestern University Feinberg School of Medicine

 
September 2012
UHRF1 Protein Links Two Types of Epigenetic Modification Link to external Web site
September 30, 2012 • University of North Carolina Health Care

Induced Pluripotent Stem Cells and Cancer Cells Found to Be Similar Link to external Web site
September 28, 2012 • University of California, Davis

New Way of Fighting High Cholesterol Upends Assumptions Link to external Web site
September 27, 2012 • University of California, San Diego

New NSF-NIH-USDA-BBSRC Grants Fund Research on How Infectious Diseases Are Transmitted Link to external Web site
September 27, 2012 • National Science Foundation

Protein Structure Unlocks Mystery of Multi-Drug Tolerance Link to external Web site
September 26, 2012 • Duke University Medical Center

Potassium Channel Helps Drive Daily Rhythms in Neuronal Activity Link to external Web site
September 25, 2012 • New York University

Newly Discovered Molecule Could Deliver Drugs to Treat Diseases Link to external Web site
September 24, 2012 • Kansas State University

Environmental Stress Response Different in Nearly Genetically Identical Microorganisms Link to external Web site
September 24, 2012 • North Carolina State University

Team Develops Editing Toolkit for Customizing Zebrafish Genomes Link to external Web site
September 23, 2012 • Mayo Clinic

Discovery Sheds Light on How a Human Anti-HIV Mechanism Works Link to external Web site
September 23, 2012 • University of California, San Diego

New Centers to Study HIV’s Basic Biology, Drug Resistance
September 21, 2012 • National Institute of General Medical Sciences

Transcriptional Profiling Reveals Insights Into Migrating Cells Link to external Web site
September 20, 2012 • California Institute of Technology

Small RNAs Help Silence Mobile Genetic Elements in Germline Cells Link to external Web site
September 20, 2012 • Cold Spring Harbor Laboratory

New Center at Scripps Research Institute to Shed Light on HIV Drug Resistance Link to external Web site
September 19, 2012 • The Scripps Research Institute

Engineered Nanoparticles Deliver Drugs to Mitochondria Link to external Web site
September 19, 2012 • University of Georgia

Study Uncovers Epigenetic Signature of Induced Pluripotent Stem Cells Link to external Web site
September 18, 2012 • Salk Institute for Biological Studies

New Method for Reversibly Tagging Proteins Link to external Web site
September 16, 2012 • University of California, San Diego

Flu Antibody's 'One-Handed Grab' May Boost Universal Vaccine Effort Link to external Web site
September 16, 2012 • The Scripps Research Institute

First 3-D Model of a Protein Complex Critical to Embryonic Development Link to external Web site
September 14, 2012 • Lawrence Berkeley National Laboratory

Two Key Genes Direct Muscle Fiber Differentiation Link to external Web site
September 13, 2012 • Uni­ver­sity of New Mex­ico

Loss of Epigenetic Mark is a Red Flag for Deadly Skin Cancer Link to external Web site
September 13, 2012 • Brigham and Women's Hospital

Intestinal Microbes Help the Body Absorb Dietary Fats Link to external Web site
September 12, 2012 • University of North Carolina Health Care

Top U.S. Science Prize Recognizes NIGMS-Funded Basic Research
September 11, 2012 • National Institute of General Medical Sciences

"Molecular Beacons" Track Stem Cell Transformation Link to external Web site
September 11, 2012 • Brown University

Study Provides Insight Into How Widespread Class of Proteins Senses Oxygen Link to external Web site
September 10, 2012 • University of Georgia

NIGMS Funds First IDeA Grants for Clinical and Translational Research
September 10, 2012 • National Institute of General Medical Sciences

Study Identifies Genes Associated With Genomic Expansions That Cause Disease Link to external Web site
September 9, 2012 • Georgia Institute of Technology

Well-Known Protein Reveals New Tricks Link to external Web site
September 6, 2012 • University of Califormia, San Francisco

Scientists Design Molecule That Reverses Some Fragile X Syndrome Defects Link to external Web site
September 4, 2012 • The Scripps Research Institute

RNA Binding Protein's Potential Targets Found to be in the Thousands Link to external Web site
September 4, 2012 • University of California, San Diego

New Mass Spectrometry Approach Could Speed Drug Discovery Link to external Web site
September 3, 2012 • Pacific Northwest National Laboratory

Computational Model Offers Tool for Predicting Anti-HIV Therapy Outcome Link to external Web site
September 2, 2012 • Harvard University

Ancient Enzymes Function Like Nanopistons to Unwind RNA Link to external Web site
September 2, 2012 • The University of Texas at Austin

 
August 2012
Microscopy Technique Yields First Measure of Key Cardiac Protein's Flexibility Link to external Web site
August 31, 2012 • Florida State University

Wound Repair in Flatworms May Help Guide Regenerative Therapies in Humans Link to external Web site
August 30, 2012 • Stowers Institute for Medical Research

Study Shows 'Promiscuous' Metabolic Enzymes Still Prevalent Link to external Web site
August 30, 2012 • University of California, San Diego

Study Reveals Neuronal Protein's Role in Cell Adhesion and Migration Link to external Web site
August 30, 2012 • University of North Carolina Health Care

Genetic Variation Influences Complex Trait and Survival in Natural Setting Link to external Web site
August 30, 2012 • Duke University

Ancient Genome Reveals Its Secrets Link to external Web site
August 30, 2012 • Max Planck Institute for Evolutionary Anthropology

"Noise" in Signals That Control Transcription Linked to Gene Organization Link to external Web site
August 30, 2012 • Rice University

Computational Model Provides Tool for Exploring How Genes Control Embryonic Development Link to external Web site
August 28, 2012 • California Institute of Technology

Repressor Proteins Turn Down Gene Activities by Thwarting Histone Link to external Web site
August 27, 2012 • Stowers Institute for Medical Research

Cap Recycling Enables mRNAs to be Stored and Reactivated Link to external Web site
August 27, 2012 • Ohio State University

Quantitative Approach Reveals Characteristics of On-Off Genetic Switch Link to external Web site
August 23, 2012 • Emory University

Professor Terrance Cooper of The University of Tennessee Health Science Center Receives $1.4 Million Grant for Biomedical Research Link to external Web site
August 23, 2012 • University of Tennessee

Histone-Modifying Proteins - Not Histones - Hold on to DNA During Replication Link to external Web site
August 23, 2012 • Thomas Jefferson University

Addition of Sugar Molecule to Metabolic Enzyme Feeds Tumor Growth Link to external Web site
August 23, 2012 • California Institute of Technology

Structure of Gene Regulator Reveals Clues to Drug Resistance in Tuberculosis Link to external Web site
August 22, 2012 • Iowa State University

NIH Uses Genome Sequencing to Track Hospital Bacterial Outbreak Link to external Web site
August 22, 2012 • National Human Genome Research Institute

Methylation Enzyme Uses Two-Pronged Approach to Control Gene Activity Link to external Web site
August 22, 2012 • Stowers Institute for Medical Research

Study Reveals Unique Solution to Controlling Potentially Deleterious Genes Link to external Web site
August 21, 2012 • Benaroya Research Institute

Enzyme Plays Crucial Role in Preserving 'Stem-ness' of Stem Cells Link to external Web site
August 21, 2012 • University of Michigan

Common Antifungal Drug Slows Tumor Growth Link to external Web site
August 21, 2012 • The University of Texas at Austin

Automated Worm Sorter Speeds Search for Genes That Affect Development Link to external Web site
August 19, 2012 • Georgia Institute of Technology


 
This page last reviewed on February 11, 2013