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Clinical Trials
The National Heart, Lung, and Blood Institute (NHLBI) is strongly committed to supporting research aimed at preventing and treating heart, lung, and blood diseases and conditions and sleep disorders.
NHLBI-supported research has led to many advances in medical knowledge and care. However, many questions remain about various diseases and conditions, including high blood pressure (HBP).
The NHLBI continues to support research aimed at learning more about HBP. For example, NHLBI-supported research on HBP includes studies that explore:
- How HBP and its treatments affect brain function in children
- Behavioral approaches to HBP treatment in adults
- The relationship between stress, ethnicity, and blood pressure
- How much blood pressure needs to be lowered to reduce the risk of stroke, heart disease, and other health problems in adults who have HBP
- How certain medicines and therapies can help treat and control blood pressure
Much of this research depends on the willingness of volunteers to take part in clinical trials. Clinical trials test new ways to prevent, diagnose, or treat various diseases and conditions.
For example, new treatments for a disease or condition (such as medicines, medical devices, surgeries, or procedures) are tested in volunteers who have the illness. Testing shows whether a treatment is safe and effective in humans before it is made available for widespread use.
By taking part in a clinical trial, you can gain access to new treatments before they're widely available. You also will have the support of a team of health care providers, who will likely monitor your health closely. Even if you don't directly benefit from the results of a clinical trial, the information gathered can help others and add to scientific knowledge.
If you volunteer for a clinical trial, the research will be explained to you in detail. You'll learn about treatments and tests you may receive, and the benefits and risks they may pose. You'll also be given a chance to ask questions about the research. This process is called informed consent.
If you agree to take part in the trial, you'll be asked to sign an informed consent form. This form is not a contract. You have the right to withdraw from a study at any time, for any reason. Also, you have the right to learn about new risks or findings that emerge during the trial.
For more information about clinical trials related to HBP, talk with your doctor. You also can visit the following Web sites to learn more about clinical research and to search for clinical trials:
- http://clinicalresearch.nih.gov
- www.clinicaltrials.gov
- www.nhlbi.nih.gov/studies/index.htm
- www.researchmatch.org
For more information about clinical trials for children, visit the NHLBI's Children and Clinical Studies Web page.
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Managing High Blood Pressure With Lifestyle Changes Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. To find clinical trials that are currently underway for High Blood Pressure, visit www.clinicaltrials.gov.
October 10, 2012
NIH grantees win 2012 Nobel Prize in Chemistry
The 2012 Nobel Prize in chemistry has been awarded to National Institutes of Health grantees Robert J. Lefkowitz, M.D., of the Howard Hughes Medical Institute and Duke University Medical Center, Durham, N.C.; and Brian K. Kobilka, M.D., of the Stanford University School of Medicine, Stanford, Calif., for studies of protein receptors that let body cells sense and respond to outside signals.
The NHLBI updates Health Topics articles on a biennial cycle based on a thorough review of research findings and new literature. The articles also are updated as needed if important new research is published. The date on each Health Topics article reflects when the content was originally posted or last revised.
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