National Institutes of Health
- The primary NIH organization for research on Osteonecrosis is the National Institute of Arthritis and Musculoskeletal and Skin Diseases
Osteonecrosis occurs when your bones lose their blood supply. The bones die and eventually collapse, leading to pain and arthritis. You can have osteonecrosis in one or several bones. It is most common in the upper leg. Other common sites are your upper arm and your knees, shoulders and ankles. The disease can affect men and women of any age, but it usually strikes in your thirties, forties or fifties.
Early in the disease you might not have any symptoms. Later, you will probably have joint pain that becomes more severe as the disease gets worse.
No one is sure what causes the disease. Risk factors include
Treatments include medicines, using crutches, limiting activities that put weight on the affected joints, electrical stimulation and surgery.
NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
References and abstracts from MEDLINE/PubMed (National Library of Medicine)