Knockout Mouse Phenotyping

Program Snapshot

The Common Fund’s Knockout Mouse Phenotyping Program (KOMP2) provides broad, standardized phenotyping of a genome-wide collection of mouse knockouts generated by the International Knockout Mouse Consortium (IKMC), funded by the NIH, European Union, Wellcome Trust, Canada, and the Texas Enterprise Fund.

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Program Highlights

KOMP2 Program Makes First Awards
Seven new projects receive NIH Common Fund support in fiscal year 2011 via the KOMP2 program. The program is creating a valuable genetic resource for revealing mammalian gene function, providing insight into genes that affect human health and disease.

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International Mouse Phenotyping Consortium (IMPC) Policies

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KOMP2 phenotyping Scheme

Diagram showing overview of the KOMP2 phenotyping process. Building on resources derived from IKMC, standardized phenotyping of mutant mouse strains will be performed and data stored in a centralized database.
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Division of Program Coordination, Planning, and Strategic Initiatives  •  National Institutes of Health  •  Bethesda, Maryland 20892