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NCI Dictionary of Cancer Terms

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memantine hydrochloride  listen  (MEH-mun-teen HY-droh-KLOR-ide)

  A drug used to treat dementia caused by Alzheimer disease. It is also being studied in the treatment of side effects from whole-brain radiation therapy for cancer and other conditions. Memantine hydrochloride blocks the uptake of calcium by certain brain cells and decreases their activity. It is a type of N-methyl-D-asparatate (NMDA) receptor antagonist. Also called Namenda.