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tetradecanoylphorbol acetate
A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic cell lines, including leukemic cells. This agent may induce gene expression and protein kinase C (PKC) activity. In addition to potential antineoplastic effects, TPA may exhibit tumor promoting activity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | Lonomycin Phorbol Myristate Acetate | |
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| Abbreviations: | | PMA TPA | |
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| Chemical structure: | | 12-O-tetradecanoylphorbol-13-acetate | |
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