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pentamethylmelamine
A principal metabolite of hexamethylmelamine with antineoplastic activity. Pentamethylmelamine alkylates DNA and other macromolecules and forms DNA intrastrand and DNA-protein crosslinks, thereby preventing DNA replication. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Abbreviation: | | PMM | |
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| Chemical structure: | | N,N,N',N',N"-pentamethyl-1,3,5-triazine | |
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