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piperazinedione
A crystalline antibiotic fermentation product isolated from the bacterium Streptomyces griseoluteus with antineoplastic activity. Piperazinedione alkylates DNA at the N-7 position of guanine, inhibiting DNA replication and inducing cell cycle arrest. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | compound 593A Merck Compound 593A; | |
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| Abbreviation: | | PZD | |
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| Code name: | | 593A | |
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