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sodium salicylate
The sodium salt of salicylic acid. As a nonsteroidal anti-inflammatory drug (NSAID), sodium salicylate irreversibly acetylates cyclooxygenases I and II, thereby inhibiting prostaglandin synthesis and associated inflammation and pain. This agent may also activate mitogen-activated protein kinase (p38MAPK), thereby inducing apoptosis in cancer cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | salicylate salicylic acid salsalate | |
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| US brand name: | | Disalcid | |
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| Abbreviation: | | Na-Sal | |
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| Chemical structure: | | benzoic acid, 2-hydroxy-, monosodium salt | |
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