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apolizumab
A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | 1D1O Anti-lymphoma Antibody Monoclonal antibody 1D10 Monoclonal Antibody Hu1D10 | |
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| US brand name: | | Remitogen | |
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| Abbreviations: | | MOAB 1D10 MoAb Hu1D10 | |
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