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yttrium Y 90 clivatuzumab tetraxetan
A radioimmunoconjugate comprised of the humanized monoclonal antibody HuPAM4, directed against the pancreatic cancer antigen MUC1, that is conjugated to the chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and radiolabeled with the beta-emitting radioisotope Yttrium Y90. Yttrium Y 90 clivatuzumab tetraxetan binds to tumor cells expressing MUC1 antigen, selectively delivering a cytotoxic dose of beta radiation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | yttrium Y 90 DOTA monoclonal antibody HuPAM4 | |
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| Abbreviation: | | Y90 DOTA MOAB HuPAM4 | |
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