ALTBIB, Bibliography on Alternatives to Animal Testing

ALTWEB , Alternatives to Animal Testing - Refinement, Reduction and Replacement

Animal Use Alternative Thesaurus, National Agricultural Library, USDA

Center for Alternatives to Animal Testing  (CAAT), Johns Hopkins University, School of Public Health

Center for Animal Alternatives , University of California at Davis

Information Resources for Adjuvants and Antibody Production: Comparisons and Alternative Technologies 1990-1997, Animal Welfare Information Center, USDA  

Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)

NICEATM-ICCVAM Five-Year Plan, alternative test methods.

NICEATM and ICCVAM Test Method Evaluations

Norwegian Reference Centre for Laboratory Animal Science and Alternatives

TSAR , Tracking System for Alternative Test Methods Review, Validation and Approval, European Commission

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AGRICOLA (AGRICultural OnLine Access), USDA

PUBMED, National Library of Medicine

TOXNET, National Library of Medicine

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Animal Ethics Infolink , Australia

Guidelines for the Ethical Conduct in the Care and Use of Animals , APA

Information Resources for Institutional Animal Care and Use Committees 1985-1999: Ethics, USDA

NASA Principles for the Ethical Care and Use of Animals

National Health and Medical Research Council  (NHMRC), Australia

NIH Bioethics Resources on the Web: Research Ethics, Laboratory Animal Care and Use

On Being a Scientist: Responsible Conduct in Research , 1995, NAP

The Principles of Humane Experimental Technique , W.M.S. Russell and R.L. Burch, 1959, Johns Hopkins University, School of Public Health

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Animal and Plant Health Inspection Service (APHIS), USDA

Animal Care, APHIS, USDA 

Animal Welfare Information Center (AWIC), National Agricultural Library, USDA

Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM)

National Institutes of Health (NIH)

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Animal Care Policy Manual, APHIS, USDA

Animal Welfare Act

Animal Welfare Regulations (9CFR Chapter 1)

Compliance with the NIH Guidelines for Research Involving Recombinant DNA Molecules

Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES)

Health Research Extension Act of 1985, Public Law 99-158 "Animals in Research"

NASA Principles for the Ethical Care and Use of Animals

NIH Revitalization Act of 1993, Public Law 103-43, "Plan for Use of Animals in Research" (PDF - 22 KB)

OSHA Standards on Bloodborne Pathogens and Needlestick Prevention

OSHA Standards on Occupational Exposure to Hazardous Chemicals in Laboratories

Public Health Service Policy on Humane Care and Use of Laboratory Animals

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Academy of Surgical Research  (ASR)

American Association for Laboratory Animal Science  (AALAS)

American College of Laboratory Animal Medicine (ACLAM)

American Society of Laboratory Animal Practitioners (ASLAP)

American Veterinary Medical Association (AVMA)

Americans for Medical Progress  (AMP)

Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International)

Australian and New Zealand Council for the Care of Animals in Research and Teaching  (ANZCCART)

Canadian Association for Laboratory Animal Science  (CALAS)

Canadian Council on Animal Care  (CCAC)

Federation of Animal Science Societies  (FASS)

Foundation for Biomedical Research  (FBR)

Institute for Laboratory Animal Research  (ILAR), National Research Council, National Academy of Sciences

Laboratory Animal Management Association  (LAMA)

National Centre for the Replacement, Refinement and Reduction of Animals in Research  (NC3Rs)

Public Responsibility in Medicine and Research  (PRIM&R)

Scientists Center for Animal Welfare  (SCAW)

States United for Biomedical Research  (SUBR)

Understanding Animal Research

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General

• For the Greater Good - 5 part Seattle Post-Intelligencer series , 2000
• Guide for the Care and Use of Laboratory Animals , 2011, ILAR 
• International Guiding Principles for Biomedical Research Involving Animals , CIOMS
• NIH Plan for the Use of Animals in Research

Animal Facilities

• Cost Analysis and Rate Setting Manual (PDF - 529 KB), NIH
• Guidelines for the Humane Transportation of Research Animals , 2006, ILAR 
• NIH Design Policy and Guidelines
• Strategies That Influence Cost Containment in Animal Research Facilities , 2000, ILAR

Biosafety

• Biosafety in Microbiological and Biomedical Laboratories (BMBL), 2009, CDC

Education

• A Guide for Developing Educational and Training Programs , 1991, ILAR
• Principles and Guidelines for the Use of Animals in Precollege Education  (PDF - 244 KB), 1991, ILAR
• Swimming with the Tide: Animal Welfare in Veterinary Medical Education and Research , JVME, Vol. 37, No. 1
• VAS Factsheet (PDF - 130 KB)
• What Investigators Need to Know about the Use of Animals (PDF - 4 MB)

Euthanasia

• AVMA Guidelines on Euthanasia, 2007 (PDF - 1 MB)

Journals and Books

• IACUC Guidebook (PDF - 3.2 MB), 2002, ARENA/OPRR
• Lab Animal
• Laboratory Animals: The International Journal of Laboratory Animal Science and Welfare
• National Academies Press
• Resource Book for the Design of Animal Exercise Protocols , 2006, APS

Occupational Health and Safety

• Criteria for a Recommended Standard: Occupational Exposure to Waste Anesthetic Gases and Vapors, 1977, CDC
• Occupational Health and Safety in the Care and Use of Nonhuman Primates , 2003, ILAR
• Occupational Health and Safety in the Care and Use of Research Animals , 1997, ILAR

Pain and Distress

• Definition of Pain and Distress and Reporting Requirements for Laboratory Animals: Proceedings of the Workshop Held 6/22/00 , ILAR
• Recognition and Alleviation of Distress in Laboratory Animals, 2008, ILAR
• Recognition and Alleviation of Pain in Laboratory Animals, 2009, ILAR

Research Related

• Corrositex®: An in vitro Test Method for Assessing Dermal Corrosivity Potential of Chemicals, ICCVAM 
• Essentials for Animal Research , B. T. Bennett, M. J. Brown and J. C. Schofield
• Guidance for the Description of Animal Research in Scientific Publications , 2011, ILAR 
• Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research, 2003, ILAR
• Monoclonal Antibody Production (PDF - 337 KB), 1999, ILAR
• National Toxicology Program (NTP)

Species Specific

• Chimpanzees in Biomedical and Behavioral Research: Assessing the Necessity, 2011, IOM
• Chimpanzees in Research - Strategies for their Ethical Care, Management and Use , 1997, ILAR 
• Guide for the Care and Use of Agricultural Animals in Research and Teaching , 2010, FASS
• Guidelines for the Use of Fishes in Research  (PDF - 735 KB), 2004, AFS
• Guidelines for Use of Live Amphibians and Reptiles in Field and Laboratory Research  (PDF - 92 KB), 2004, ASIH
• Guidelines of the American Society of Mammalogists for the Use of Wild Mammals in Research , 2011, ASM
• Guidelines on the Care and Use of Wildlife  (PDF - 1.1 MB), 2003, CCAC
• Guidelines to the Use of Wild Birds in Research , 2010, The Ornithological Council
• Psychological Well-Being of Nonhuman Primates , 1998, ILAR 
• Scientific and Humane Issues in the Use of Random Source Dogs and Cats in Research, 2009, ILAR

Veterinary Care

• ACLAM Guidelines on Adequate Veterinary Care (PDF - 148 KB)
• Merck Veterinary Manual

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Comparison of Federal Requirements and Policies (PDF - 57 KB)

Disaster Planning and Response Resources, OLAW

Disaster Response, NIH

IACUC.ORG

International Veterinary Information Service  (IVIS)

Link Animal Models to Human Disease  (LAMHDI)

Model Organisms for Biomedical Research, NIH

NETVET Veterinary Resources , Washington University

Nonhuman Primate Enrichment and Social Housing, OLAW

Primate Enrichment Forum

Primate Info Net

Primate Portal

Statistical Calculations Resource

Timeline of Laws Related to Animal Subjects, NIH

Zebrafish International Resource Center  (ZIRC)

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AALAS Learning Library

Assessing the Health and Welfare of Laboratory Animals  (AHWLA), Newcastle University

Certificate in Laboratory Animal Medicine , University of Guelph

Collaborative Institutional Training Initiative  (CITI)

The Experimental Fish , University of Prince Edward Island

How to Write an Application Involving Research Animals, NIH

Institutional Animal User Training Program , CCAC

Laboratory Animal Training Association  (LATA)

Laboratory Animal Welfare Training Exchange  (LAWTE)

PHS Policy on Humane Care and Use of Laboratory Animals Tutorial, OLAW

Training in Survival Rodent Surgery (Part I  | Part II ), IVIS

Videos

• Working Safely with Nonhuman Primates
• Working with the Laboratory Dog
• Mouse & Rat Humane Restraint and Experimental Techniques
• Training in Survival Rodent Surgery
• Training in Basic Biomethodology for Laboratory Mice
• Training in Basic Biomethodology for Laboratory Rats

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Please e-mail suggested links and comments to OLAW: olaw@od.nih.gov

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