Funding for Special   Communities

Genetics & Genomics

The primary emphasis of the general Genetics and Genomics Program is on studies that develop genomics and genetics tools for humans and model organisms, including the non-mammalian model organisms such as zebrafish, Drosophila, C. elegans, Xenopus and yeast. Relevant studies include development of

  • Statistical techniques for mapping quantitative trait loci (QTLs) or genes contributing to complex traits, including haplotype mapping of kidney, urologic, or hematologic traits
  • Microarray and other high-throughput genomics and proteomics technologies
  • Genomic analysis of humans, zebrafish, and other model organisms
  • Development of genomics tools for creation of transgenic or knockout animals
  • Genome-anatomy projects focusing on renal or urologic tissues or progenitor cells.

Renal Genetics and Genomics

The primary emphasis of the Renal Genetics and Genomics Program is on studies that use genomics and genetics approaches to elucidate the normal and pathologic function of the kidney, including the renal consequences of diseases such as diabetes, hypertension, and ischemia, kidney development and growth, and cyst formation in the kidney. Relevant studies include

  • Genetics studies of normal kidney development or kidney disease, such the elucidation of the inheritability or molecular genetic basis of single-gene or genetically complex familial diseases in humans
  • Identification and characterization of quantitative trait loci or of modifier loci affecting single gene traits in humans or animal models
  • Mutagenesis and mutant screens in model organisms
  • Genotype-phenotype correlations in humans and animal models In addition, the program includes
  • Genomics- and proteomics-based nephrology studies, such as novel tools for tissue-specific gene expression or site-directed mutagenesis in animal models
  • Microarray-based genotyping or expression studies
  • High-throughput characterization of tissue-specific gene or protein expression patterns
  • High-throughput characterization of tissue-specific protein-protein interactions

Urology Genetics and Genomics

The primary emphasis of the Urology Genetics and Genomics Program is on studies that use genomics and genetics approaches to elucidate the normal and pathologic function of the urinary and urogenital tracts. Relevant studies include

  • Urology genetics studies, such the elucidation of the inheritability or molecular genetic basis of single-gene or genetically complex familial diseases in humans
  • Identification and characterization of quantitative trait loci or of modifier loci affecting single-gene traits in humans or animal models
  • Mutagenesis and mutant screens in model organisms
  • Genotype-phenotype correlations in humans and animal models
In addition, the program includes genomics- and proteomics-based urology studies, such as
  • Development of novel tools for tissue-specific gene expression or site-directed mutagenesis in animal models
  • Microarray-based genotyping or expression studies
  • High-throughput characterization of tissue-specific gene or protein expression patterns
  • High-throughput characterization of tissue-specific protein-protein interactions

For more information, contact Dr. Rebekah Rasooly, Program Director, Genetics and Genomics or Dr. Paul Kimmel, Program Director, Kidney Translational Genetics.

Resources for Researchers

Clinical Research

Centers

  • O'Brien Kidney and Urology Research Centers - Overview & Map
  • Polycystic Kidney Disease Research & Translation Centers - Overview & Map
  • Research Centers of Excellence in Pediatric Nephrology - Overview & Map

Committees and Advisory Groups

Related Study Sections

NIDDK Staff

  • Dr. Lawrence Agodoa, Director, Office of Minority Health Research Coordination
  • Dr. Paul Eggers, Program Director, Epidemiology and U.S. Renal Data System; End-Stage Renal Disease
  • Dr. Michael Flessner, Program Director, Clinical Chronic Kidney Disease; Inflammatory Kidney Disease; Clinical PKD; PKD Centers
  • Dr. Deborah Hoshizaki, Program Director, Kidney Development; Kidney and Regeneration and Repair
  • Dr. Chris Ketchum, Deputy Director, KUH Basic Science and Program Director, Kidney Basic Physiology
  • Dr. Paul L. Kimmel, Program Director, Clinical Acute Kidney Injury; Kidney Translational Genetics; Kidney HIV/AIDS
  • Dr. John Kusek, Program Director, Kidney Clinical Trials
  • Dr. Marva Moxey-Mims, Deputy Director, KUH Clinical Science and Program Director, Pediatric Nephrology and Urology; Kidney Centers; Kidney Small Business
  • Dr. Andrew Narva, Director, National Kidney Disease Education Program and Program Director, Kidney Education and Translation
  • Dr. Tracy Rankin, Program Director, Kidney Training and Career Development
  • Dr. Rebekah Rasooly, Program Director, Genetics and Genomics; Basic PKD
  • Dr. Krystyna Rys-Sikora, Program Director, Basic Acute Kidney Injury; Basic Chronic Kidney Disease
  • Dr. Robert Star, Director, Division of Kidney, Urologic, and Hematologic Diseases

Funding Opportunities

Funding for Special Communities

Conferences

Related Reports

Related Organizations

See Also



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Page last updated: September 15, 2010

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