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NCI Drug Dictionary


xenogeneic tyrosinase DNA vaccine 
A plasmid DNA vaccine, encoding an epitope of mouse tyrosinase, with potential antineoplastic activity. Administered via intramuscular electroporation, vaccination with xenogeneic tyrosinase DNA vaccine may induce both humoral and cytotoxic lymphocyte (CTL) immune responses against melanoma cells that express tyrosinase, resulting in decreased tumor growth. . Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)