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golnerminogene pradenovec
A recombinant agent consisting of a genetically-modified adenovirus 5 vector encoding the protein cytokine tumor necrosis factor (TNF) alpha. TNF exhibits potent anti-tumor cytolytic properties; the adenovirus 5 vector efficiently infects tumor cells, delivering tumor-specific TNF. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | adenovirus 5-tumor necrosis factor alpha AdGV11-TNFalpha tumor necrosis factor adenovirus 5 vector | ||
US brand name: | TNFerade | ||
Abbreviations: | Ad 5-TNF Alpha Ad5-TNFa | ||
Code name: | ADgv EGR.TNF.11D | ||