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bromodeoxyuridine
A halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and the inhibition of cell proliferation. As a radiosensitizer, this agent is associated with the inhibition of repair of radiation-induced DNA double-strand breaks (DSBs). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | 5-bromodeoxyuridine broxuridine | |
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| Abbreviations: | | 5-BrdU BrdU | |
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| Chemical structure: | | 5-bromouracil-2-deoxyriboside | |
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