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lobradimil
A synthetic analog of bradykinin. Lobradimil is a potent, specific bradykinin B-2 receptor agonist that stimulates B-2 receptors expressed on the surface of brain capillary endothelial cells, thereby reversibly increasing the permeability of the blood-brain barrier (BBB). Compared to bradykinin, this agent possesses enhanced receptor selectivity, greater plasma stability, and a longer half-life. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | RMP-7 | |
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| US brand name: | | Cereport | |
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| Code name: | | DRG-0182 | |
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| Chemical structures: | | L-Prolinamide, L-Arginyl-L-prolyl-trans-4- hydroxy-L-prolyl-3-(2- thienyl)-L-alanylglycl -L-seryl-N-(2-((4-((aminoiminomethyl)amino)-1- -carboxybutyl)amino)-1-((4-methoxyphenyl)methyl)ethyl)-, (S-(R*,R*)) L-Prolinamide,L-Arginyl-L-protyl-trans-4-hydroxy-L-prolyl-3-(2-thienyl)-L-alanylglycyl-L-seryl-N-02-004-0(aminoiminomethyl)amino)-1-0(4-methoxyphenyl)methyl)ethyl)-,0S-(R*,R*)) | |
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