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chlorambucil
An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | chlorambucilum chloraminophen Chlorbutin chlorbutine chlorbutinum chloroambucil chlorobutin chlorobutine Leukersan Leukoran Lympholysin phenylbutyric acid nitrogen mustard | |
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| US brand names: | | Ambochlorin Amboclorin Leukeran Linfolizin | |
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| Foreign brand names: | | Alti-chlorambucil Chloraminophene Linfolysin | |
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| Abbreviations: | | CHL CLB | |
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| Code names: | | CB-1348 WR-139013 | |
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| Chemical structures: | | 4-[bis(2-chloroethyl)amino]benzenebutanoic acid 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid benzenebutanoic acid, 4-[bis(2-chloroethyl)amino]- (9CI) butyric acid, 4-(p-bis(2-chloroethyl)aminophenyl) gamma-(p-bis(2-chloroethyl)aminophenyl)butyric acid gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid N,N-di-2-chloroethyl-gamma-p-aminophenylbutyric acid p-(N, N-di-2-chloroethyl)aminophenyl butyric acid para-N,N-di(b-chloroethyl)aminophenylbutyric acid p-N, N-di-(beta-chloroethyl)aminophenyl butyric acid | |
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