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N-methylformamide
A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | formylmethylamine monomethylformamide | |
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| Abbreviation: | | NMF | |
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| Code names: | | EK 7011 X 188 | |
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