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satraplatin
An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in cell growth inhibition and apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| US brand name: | | Orplatna | |
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| Code names: | | BMS-182751 BMY-45594 JM216 | |
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| Chemical structures: | | (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43) | |
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