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altretamine
A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | Hemel Hexaloids | |
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| US brand names: | | Hexalen hexamethylmelamine | |
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| Foreign brand names: | | Hexastat Hexinawas | |
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| Abbreviations: | | HMM HXM | |
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| Code names: | | ENT-50852 RB-1515 WR-95704 | |
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| Chemical structures: | | 2,4,6-tris(dimethylamino)-s-triazine N,N,N',N',N",N"-hexamethyl-1,3,5-triazine-2,4,6-triamine | |
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