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iodine I 131 rituximab
A radioimmunoconjugate comprised of rituximab, a recombinant chimeric monoclonal antibody directed against the CD20 antigen, and labeled with iodine I 131 with potential antineoplastic activity. The antibody moiety of iodine I 131 rituximab binds to the CD20 antigen thereby delivering cytotoxic iodine I 131 specifically to cancer cells expressing CD20. The CD20 antigen, a hydrophobic transmembrane protein, is expressed on normal pre-B and mature B lymphocytes. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | (131)I-rituximab 131I-Rituxan 131I-rituximab | |
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