Do not take lisinopril and hydrochlorothiazide if you are pregnant. If you become pregnant while taking lisinopril and hydrochlorothiazide, call your doctor immediately. Lisinopril and hydrochlorothiazide may harm the fetus.
The combination of lisinopril and hydrochlorothiazide is used to treat high blood pressure. Lisinopril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly. Hydrochlorothiazide is in a class of medications called diuretics ('water pills'). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.
The combination of lisinopril and hydrochlorothiazide comes as a tablet to take by mouth. It is usually taken once a day with or without food. To help you remember to take lisinopril and hydrochlorothiazide, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lisinopril and hydrochlorothiazide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Lisinopril and hydrochlorothiazide controls high blood pressure but does not cure it. Continue to take lisinopril and hydrochlorothiazide even if you feel well. Do not stop taking lisinopril and hydrochlorothiazide without talking to your doctor.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Talk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-salt or low-sodium diet, or an exercise program, follow these directions carefully.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
dizziness
headache
cough
excessive tiredness
pain, burning, or tingling in the hands or feet
decrease in sexual ability
heartburn
swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
hoarseness
difficulty breathing or swallowing
stomach pain
upset stomach
vomiting
fever, sore throat, chills, and other signs of infection
muscle pain, cramps, or weakness
yellowing of the skin or eyes
dry mouth
thirst
weakness
restlessness
confusion
seizures
decrease in urination
lightheadedness
fainting
chest pain
rapid, pounding, slow, or irregular heartbeat
pain in big toe
tingling in arms and legs
loss of muscle tone
weakness or heaviness in legs
lack of energy
cold, gray skin
Lisinopril and hydrochlorothiazide may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/Safety/MedWatch] or by phone [1-800-332-1088].
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
lightheadedness
fainting
blurred vision
dry mouth
thirst
weakness
drowsiness
restlessness
confusion
seizures
muscle pains or cramps
infrequent urination
upset stomach
vomiting
rapid or pounding heartbeat
Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to lisinopril and hydrochlorothiazide. Your doctor may order certain lab tests to check your body's response to lisinopril and hydrochlorothiazide.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking lisinopril and hydrochlorothiazide.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Last Revised - 09/15/2012
AHFS® Consumer Medication Information. © Copyright, 2012. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.