Trastuzumab

  (tras-TOO-zoo-mab)

This page contains brief information about trastuzumab and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s):		Herceptin
FDA Approved:		Yes

FDA Approval for Trastuzumab

Trastuzumab is approved to be used alone or with other drugs to treat:

• Adenocarcinoma of the stomach or gastroesophageal junction. It is used for HER2 positive (HER2+) disease that has metastasized (spread to other parts of the body) in patients who have not already been treated for metastatic cancer.

• Breast cancer that is HER2+. It is used in patients whose disease has not gotten better with other chemotherapy.

Trastuzumab is also being studied in the treatment of other types of cancer.

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Trastuzumab - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Targeted Cancer Therapies - Information about the use of this drug to treat cancer.

The ALTTO (Adjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Breast Cancer Trial - Information about a major NCI-supported clinical trial for this drug.

Clinical Trial Results: For Some Breast Cancers, New Drug May Be Treatment Option - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Two Drugs That Hit One Target Show Efficacy Against Metastastic Breast Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy Less Toxic to the Heart May Be Option for Some Women with HER2-Positive Breast Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Trastuzumab after Chemotherapy Is Effective in HER2-Positive Breast Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results:Trastuzumab Benefits Women with Locally Advanced or Inflammatory Breast Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Breast Cancer Drug Helps Patients with Gastric Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Heart Problems From Trastuzumab Do Not Increase in the Short Term - Important clinical trial results for this drug, background information, and how the trial was done.

Find Clinical Trials for Trastuzumab - Check for trials from NCI's list of cancer clinical trials now accepting patients.

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