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About the NHLBI SBIR/STTR Program 

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs are engines of innovation for developing and commercializing novel technologies and products to promote the prevention, diagnosis, and treatment of heart, lung, blood, and sleep diseases and disorders. The NHLBI provides grant and contract funding opportunities to support small businesses performing research and development on technologies related to the mission of NHLBI.

The links on the left will assist you in finding funding opportunities, resources, and help related to the NHLBI SBIR/STTR program.

What's New?

Free Market Analysis for Phase I Awardees: The NIH Niche Assessment Program provides SBIR/STTR Phase I awardees with a comprehensive market analysis report that can jump start your business and inform your Phase II application. This is a free program. Learn more...

2013 Annual Contract Solicitation published: The NHLBI has nine topics in this year's solicitation, ranging from sleep to transfusion medicine and from MRI-compatible devices to nanotechnology. You can see all of our topics and the details of how to apply on our Annual Contracts page. The submission date is November 13, 2012.

New Final Progress Report Instructions: The NIH has released new instructions for preparing your SBIR/STTR Final Progress Reports. View the instructions and the Guide Notice.

2012 SBIR/STTR National Conference: Please join us for this year's SBIR/STTR National Conferenceimage of external link icon November 13-15 in Portland, OR. We will be available during the one-on-one sessions to offer advice about the NHLBI SBIR/STTR programs, funding opportunities, and resources.

Intellectual Property Assessment Tool for the USPTO: The United States Patent and Trademark Office (USPTO) has unveiled an Intellectual Property Awareness Assessment Tool, a web-based tool designed to assess intellectual property (IP) knowledge and provide personalized training resources for small and medium sized enterprises (SMEs) and inventors. If you’d care to test and/or increase your IP awareness, check out the Intellectual Property Assessment Tool.image of external link icon You can find other resources to help your small business on our Resources page.

SBIR Phase IIB Bridge Awards: The NHLBI is soliciting Phase IIB applications to accelerate the commercialization of technologies for heart, lung, blood, and sleep disorders and diseases. Learn more...

SBIR/STTR Omnibus Grant Solicitations Published: The 2012 NIH SBIR and STTR Omnibus Grant Solicitations have been published.

Commercialize NIH Technologies: The NHLBI is seeking SBIR applications for projects to transfer technologies out of the NHLBI intramural research labs into the private sector that address mechanisms, diseases, or disorders within the NHLBI mission. Read more.

Archives of What's New

Last Updated August 2012

NHLBI Bridge Award

Up to $1 million per year for three years to support the next stage of development for previously funded SBIR Phase II projects. Learn more.

SBIR-TT Program

Looking for high-quality technologies? Get funded to develop NHLBI intramural innovations. Learn more.

Unmet Needs of Particular Interest

View a list of potential SBIR/STTR research topics of particular interest to the NHLBI. Learn more.


Learn More

Sign up to receive the latest NHLBI small business program news by using the NHLBI-SBIR subscriber page on the NIH LISTSERV Web site.

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