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Pain Medication

Potential Pain Medication Targets Peripheral Nerves

Researchers report a significant advance in the search for medications that can suppress pain that currently requires opioids, but avoid opioids’ abuse potential and other undesirable CNS effects. A new compound reduces mouse responses in animal models of neurogenic and chronic inflammatory (e.g., arthritic) pain. The compound, called UB937, enhances the natural pain-killing activity of the neurotransmitter anandamide, and exerts its analgesic effects entirely in peripheral tissues, without entering the brain.

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NIH selects 11 Centers of Excellence in Pain Education

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The National Institutes of Health Pain Consortium has selected 11 health professional schools as designated Centers of Excellence in Pain Education (CoEPEs). The CoEPEs will act as hubs for the development, evaluation, and distribution of pain management curriculum resources for medical, dental, nursing and pharmacy schools to enhance and improve how health care professionals are taught about pain and its treatment. Twenty institutes, centers and offices at NIH are involved in the consortium.

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Medication-Assisted Treatment for Opioid Addiction (Topics in Brief)

April 2012
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Increase in Unintentional Overdose Deaths Involving Opioid Analgesics, 1999-2008
Methadone Treatment Pre-and Post-Release Increases Treatment Retention & Reduces Drug Use

Opioids act on specific receptors in the brain and the body, which also interact with naturally produced substances known as endorphins or enkephalins – important in regulating pain. While prescription pain relievers can be highly beneficial if used as prescribed, opioids as a general class of drugs have a high potential for abuse.

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NIDA creates easy-to-read website on drug abuse

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A new, easy-to-read website on drug abuse designed for adults with a low reading literacy level (eighth grade or below) was launched today by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.  The site, which provides plain language information on neuroscience, drug abuse prevention and treatment, is also a resource for adult literacy educators.  It has a simple design with a large default text size, motion graphic videos and other features that make it easy to read and use.

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New NIDA resource helps families navigate addiction treatment options

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A new resource, Seeking Drug Abuse Treatment: Know What to Ask, will help individuals and families struggling with addiction ask the right questions before choosing a drug treatment program.  It was developed by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, and is available to the public free online or in hard copy through NIDA’s DrugP

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Cigarette and alcohol use at historic low among teens

Cigarette and alcohol use by eighth, 10th and 12th-graders are at their lowest point since the Monitoring the Future (MTF) survey began polling teenagers in 1975, according to this year's survey results. However, this positive news is tempered by a slowing rate of decline in teen smoking as well as continued high rates of abuse of other tobacco products (e.g., hookahs, small cigars, smokeless tobacco), marijuana and prescription drugs.

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Featured Publication

Featured Publication

Drugs, Brains, and Behavior - The Science of Addiction

As a result of scientific research, we know that addiction is a disease that affects both brain and behavior.

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