September 1, 2009 This directory contains data files from the Veterans Health Administration (VHA) National Drug File Reference Terminology (NDF-RT). NDF-RT is the terminology used by FDA and the FedMed collaboration to code these essential pharmacologic properties of medications: Mechanism of Action Physiologic Effect Structural Class These three subsets are available individually at (same location): http://evs.nci.nih.gov/ftp1/FDA/ndfrt ftp://ftp1.nci.nih.gov/pub/cacore/EVS/FDA/ndfrt/ As of March 2007, the NDF-RT Public Edition is the version published for FDA, FedMed, and other purposes outside the VA system. This version contains all of the core NDF-RT concepts from previous releases, and all concept NUIs remain unchanged. The only omission is data elements deemed useful solely for internal VA operations. See the Release Notes for additional detail. Starting in January 2008, VHA has released a new version showing the logically inferred view of the terminology, rather than the directly stated (defined) assertions in the older release series. They plan to provide a description of the distinctive characteristics of this version, meanwhile released here as is for those interested. In January 2009, a major 2.0 revision was released, described in the "Changes" document and the Release Notes. In May 2009, the Public Edition added zipped Common Data Format (CDF) full and diff load packages, containing terminology information intended for importing into an Apelon DTS 3.4+ database by way of the DTS subscription import facility. The files consist of codes, name, relationships and other source-specific attributes as well as other information required by the DTS schema to maintain the integrity of the content within and among corresponding DTS namespaces. For more information on importing these files into DTS, please see the DTS Subscription Content Import Guide at http://apelon-dts.wiki.sourceforge.net/space/showimage/dtssubscriptionimport-3.4.1.pdf In August 2009, VHA and NCI produced a new Web Ontology Language (OWL) version of the complete inferred terminology. This data file will be updated on a regular basis, and will be made available for browsing and download on NCI’s public terminology browsers. In May 2010, VHA released documentation in PDF format. This file has been added to this directory. Additional information is also available at: http://www.nlm.nih.gov/research/umls/sourcereleasedocs/2008AB/NDFRT/index.html Contents - Files: Changes in NDF-RT v2.0 Public Edition.pdf (Mar 2010 revision details) NDF-RT.owl (logically inferred version in OWL) NDF-RT.txt (all codes/names: tabbed text) NDF-RT_XML.zip (full XML data file: zipped) NDF-RT_XML_Inferred.zip (logically inferred version) NDF-RT_OWL_Inferred.zip (logically inferred version in OWL, zipped) NDF-RT_Public_All.zip (all VHA release files: zipped) NDF-RT Public Edition Release Notes.txt (details on new release) NDF-RT Documentation.pdf (documentation) 77_diff__bin.zip (Apelon DTS CDF diffs: zipped) 77_full__bin.zip (Apelon DTS CDF full: zipped) ReadMe.txt (this file) Contents - Directories: Archive (dated/earlier file versions)