NIDA Notes Articles: December 2008

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Aripiprazole Prevents Rats From Resuming Cocaine Seeking

December 2008
Reports on study results indicating a medication prescribed for schizophrenia and manic phases of bipolar disorder shows promise as a cocaine addiction treatment.

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NIDA Centers Raise Physicians' Awareness of Drug Abuse Issues

December 2008
Highlights four Centers of Excellence for Physician Information designed to increase physicians' awareness of research on the medical consequences of drug abuse and addiction and incorporate research findings into clinical practice.

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New Vaccines Are Being Developed Against Addiction and Relapse

December 2008
Highlights NIDA-funded research to develop vaccines against addiction to drugs such as cocaine, nicotine, phencyclidine (PCP), and methamphetamine.

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High-Risk Drug Offenders Do Better With Close Judicial Supervision

December 2008
Reports on research showing that increasing the mandatory drug court monitoring sessions for high-risk drug offenders can enhance program success rates.

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Imaging Studies Elucidate Neurobiology of Cigarette Craving

December 2008
Reports on three separate imaging studies illuminating the neurobiology of cigarette craving.

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Long-Term Cocaine Self-Administration Depresses Brain Activity

December 2008
Discusses research exploring how widespread the reduction of neural activity is in the brain with chronic exposure to cocaine.

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Methadone Reduces Rats' Cocaine Seeking

December 2008
Reports on an animal study showing that methadone, normally used as a therapy for opioid abuse, may prove to be an effective treatment for cocaine abuse.

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Nicotine Dependence is Linked With Mental Disorders in Pregnant Women

December 2008
Reports on a link between mental disorders, including mood, anxiety, or personality disorder and nicotine dependence in pregnancy women.

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Selenium Shows Promise as an Adjunct Therapy for HIV

December 2008
Reports on a randomized controlled trial of HIV-infected men and women who, as a result of receiving selenium supplements, experienced lower HIV viral load and greater CD4 cell count.

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Brain Proteins Differ in Cocaine-Overdose Victims

December 2008
Describes research findings showing differences in protein concentrations in the brain pleasure centers of people who died from cocaine overdose as compared with those who did not abuse the drug.

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