NIDA Notes Articles: Relapse and Recovery

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Physical Activity Reduces Return to Cocaine Seeking in Animal Tests

April 2012
Two independent animal studies suggest that aerobic exercise might help cocaine abusers establish and maintain abstinence.

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Molecular Alterations of DNA Contribute to Persistence of Memory

November 2011
In a new series of studies tracing the molecular events that occur in the brain as memories are formed and preserved, researchers find that certain epigenetic changes may promote vulnerability to relapse.

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Treatment Dropout Linked With Elevated Stress Response

July 2011
Summarizes a study to determine whether a stress-related biological marker in saliva can predict how long a drug user will remain in treatment.

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Medication Reduces Rats' Return to Methamphetamine Seeking

July 2011
Reports on a new medication strategy under investigated in animal studies that shows promise for preventing relapse to drug abuse.

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Study Supports Methadone Maintenance in Therapeutic Communities

December 2010
Describes a study that examined the effectiveness of combining two therapies for drug abuse addiction: methadone treatment and therapeutic communities, two approaches that are rarely combined.

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Incentives Promote Abstinence

December 2010
Explores research findings on the value of motivational incentives to promote and reinforce abstinence from substances of abuse and encourage healthy behaviors.

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Deep Brain Stimulation Reduces Rats' Cocaine Seeking

December 2010
Describes results from an animal study involving deep brain stimulation that holds promise as a therapy for severe cocaine addiction.

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Intervention Improves Abstinence, Employment Among Welfare Recipients

December 2010
Reports research to study the effectiveness of an intensive case management program to aid female substance abusers who receive welfare in staying off drugs and finding employment.

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Program Enhances Physician Knowledge on Substance Abuse

December 2010
Reports on an evaluation of the Chief Resident Immersion Training (CRIT) program to assess its effectiveness in improving knowledge, confidence, and preparedness to diagnose, manage, and teach about substance abuse.

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New Tools and Strategies to Bolster Behavioral Therapy

October 2010
Reports on research investigating whether certain medications might strengthen patients' understanding and memory retention.

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