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Medicines By Design

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Graphic of pills How Medicines Work

Inhibitor that binds to key sites (dark blue) on the human multidrug resistance protein. Credit: John Wise, Southern Methodist University. Computation Aids Drug Discovery

Bread Mold Five Foul Things That Are Also Good for You

graphic of a frog and a molecule Nature: The Master Medicine-Maker

HIV molecule and proteins For Proteins, Form Shapes Function

Medicines By Design

Discusses the many different ways medicines work in the body and how this information guides the hunt for drugs of the future.

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Foreword: A Visit to the Doctor
Foreword: A Visit to the Doctor
Introduces the topic and the contents of each chapter. » more
Chapter 1: ABCs of Pharmacology
Chapter 1: ABCs of Pharmacology
ADME, pharmacogenetics, pharmacokinetics, dose-response curve, agonists/antagonists, grapefruit juice effect, herbals, MDR pumps » more
Chapter 2: Body, Heal Thyself
Chapter 2: Body, Heal Thyself
Aspirin's history, NSAIDs, bloodstream, antibodies, immunotherapy, CYP 450 enzymes » more
Chapter 3: Drugs from Nature, Then and Now
Chapter 3: Drugs from Nature, Then and Now
Drugs from plants, oceans and mold, statins, photodynamic therapy, toxicogenetics, chemical genetics, clinical trials » more
Chapter 4: Molecules to Medicines
Chapter 4: Molecules to Medicines
Drug delivery strategies, the "omics" revolution, G proteins, Viagra, Gleevec, anesthesia » more
Medicines for the Future
Medicines for the Future
Career options in pharmacology » more
Glossary
Glossary
Defines scientific terms used in the booklet. » more
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This page last reviewed on August 29, 2012