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    Microbiol Immunol. 2012 May;56(5):338-41. doi: 10.1111/j.1348-0421.2012.00441.x.

    Stability of toxigenicity in proteolytic Clostridium botulinum type B upon serial passage.

    Source

    Department of Microbiology, Osaka City Institute of Public Health and Environmental Sciences, 8-34 Tojo-cho, Tennoji-ku, Osaka 543-0026, Japan.

    Abstract

    Proteolytic Clostridium botulinum type B strains were investigated for stability of toxigenicity and bont/b gene upon serial passage. Strains with bont/b gene located on their plasmids showed loss or decrease of toxigenicity during serial passage. Some strains lost the bont/b gene-encoding plasmid. The stability of the plasmids varied between strains.

    © 2012 The Societies and Blackwell Publishing Asia Pty Ltd.

    PMID:
    22352877
    [PubMed - indexed for MEDLINE]

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