Skip navigation

Lymph nodes

This video plays in QuickTime format. To view the video, download and install the Apple QuickTime player at: http://www.apple.com/quicktime/download/.

The lymphatic system is a complex network of thin vessels, valves, ducts, nodes, and organs. It helps to protect and maintain the fluid environment of the body by producing, filtering, and conveying lymph and by producing various blood cells.

Lymph nodes play an important part in the body’s defense against infection. The most common cause of swollen lymph nodes is infection, which might occur even if the infection is trivial or not. Afferent lymph vessels bring unfiltered fluids into the lymph node to be filtered while efferent vessels carry clean fluids away from the lymph node and to the cardiovascular system where it helps form the plasma in the blood.

Overall, lymph nodes work like a biological filtering system. When the body is invaded by foreign organisms, the painful swelling sometimes felt in the neck, armpits, groin, or tonsils comes from the microorganisms being trapped inside collections of lymph cells or nodes. Eventually, these organisms are destroyed and eliminated by cells that line the walls of the lymph nodes and the swelling and pain subside.

Update Date: 5/15/2012

Updated by: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Related MedlinePlus Page

A.D.A.M Quality Logo

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch).

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 1997-2012, A.D.A.M., Inc. Duplication for commercial use must be authorized in writing by ADAM Health Solutions.

A.D.A.M Logo