National Institutes of Health
- The primary NIH organization for research on Islet Cell Transplantation is the National Institute of Diabetes and Digestive and Kidney Diseases
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National Institutes of Health
Islet Cell Transplantation
Islet cell transplantation places cells from an organ donor into the body of another person. It is used experimentally to treat type 1 diabetes. Islets are cells found in clusters throughout the pancreas. They are made up of several types of cells. The islets contain beta cells, which make insulin. Insulin is a hormone that helps the body use glucose for energy.
In type 1 diabetes, the beta cells of the pancreas no longer make insulin. A person who has type 1 diabetes must take insulin daily to live. Transplanted islet cells, however, can take over the work of the destroyed cells. Once implanted, the beta cells in these islets begin to make and release insulin. Researchers hope islet transplantation will help people with type 1 diabetes live without daily insulin injections.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
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Pancreatic Islet Tranplantation(National Institute of Diabetes and Digestive and Kidney Diseases)
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Pancreatic Islet Tranplantation
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Overviews
- Getting New Islet Cells(American Society of Transplantation) - PDF
- Islet Transplantation(American Diabetes Association)
- Also available in Spanish
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Clinical Trials
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ClinicalTrials.gov: Islet Cell Transplantation(National Institutes of Health)
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ClinicalTrials.gov: Islets of Langerhans Transplantation(National Institutes of Health)
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ClinicalTrials.gov: Islet Cell Transplantation
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Journal Articles
References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Immune responses against islet allografts during tapering of immunosuppression--a pilot...
- Article: The potential benefit of non-purified islets preparations for islet transplantation.
- Article: Extensive amyloid formation in transplanted microencapsulated mouse and human islets.
- Islet Cell Transplantation -- see more articles
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Directories
- Organ Procurement and Transplantation Network: Member Directory(Health Resources and Services Administration, Organ Procurement and Transplantation Network, United Network for Organ Sharing)
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Organizations
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Children
- Islet Science(Juvenile Diabetes Research Foundation International)
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