Familial Cancer Susceptibility Syndromes

Individual PDQ summaries focused on the genetics of specific cancers contain detailed information about many known cancer susceptibility syndromes. Although this is not a complete list, the following cancer susceptibility syndromes are discussed in the PDQ cancer genetics summaries:

• Basal Cell Nevus Syndrome, Gorlin Syndrome, Gorlin-Goltz Syndrome, or Nevoid Basal Cell Carcinoma Syndrome (Genetics of Skin Cancer).
• Bloom Syndrome (Genetics of Skin Cancer).
• Breast/Ovarian Cancer, Hereditary (Genetics of Breast and Ovarian Cancer).
• Colon Cancer, Hereditary Nonpolyposis or Lynch Syndrome (Genetics of Colorectal Cancer).
• Cowden Syndrome (Genetics of Breast and Ovarian Cancer; Genetics of Colorectal Cancer).
• Fanconi Anemia (Genetics of Skin Cancer).
• Hyperparathyroidism, Familial (Genetics of Medullary Thyroid Cancer).
• Li-Fraumeni Syndrome (Genetics of Breast and Ovarian Cancer).
• Medullary Thyroid Cancer, Familial (Genetics of Medullary Thyroid Cancer).
• Melanoma, Hereditary (Genetics of Skin Cancer).
• Multiple Endocrine Neoplasia Type 2A, 2B (Sipple Syndrome) (Genetics of Medullary Thyroid Cancer).
• Peutz-Jeghers Syndrome (Genetics of Colorectal Cancer; Genetics of Breast and Ovarian Cancer).
• Polyposis, Familial Adenomatous and Attenuated Familial Adenomatous Polyposis (Genetics of Colorectal Cancer).
• Polyposis, Familial Juvenile (Genetics of Colorectal Cancer).
• Polyposis, MYH-Associated (Genetics of Colorectal Cancer).
• Prostate Cancer, Hereditary (Genetics of Prostate Cancer).
• Xeroderma Pigmentosum (Genetics of Skin Cancer).