Model of the Origin Recognition Complex Bound to DNA

Cryo-electron microscopy is often used to determine the structures of large molecular complexes like the origin recognition complex (ORC), which recognizes and binds DNA to start replication, the process that copies the cell's genetic material prior to cell division. Credit: Huilin Li, Brookhaven National Laboratory and Bruce Stillman, Cold Spring Harbor Laboratory.

For more information read Study Reveals How Protein Machinery Binds and Wraps DNA to Start Replication at http://www.bnl.gov/bnlweb/pubaf/pr/PR_display.asp?prID=1391&template=Today.

National Institute of General Medical Sciences
http://www.nigms.nih.gov/

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