Pediatric Counter-Terrorism Measures

 
Anthrax

• Cipro (Ciprofloxacin Hydrochloride) Approved for Inhalation Anthrax)
  • Cipro: Approved Dosing for Children (PDF - 177KB) (labeling approved 5/18/2005)
  • Cipro (Ciprofloxacin): Use by Pregnant and Lactating Women
  • Information for Consumers on Cipro: Questions and Answers 
• Doxycycline and Penicillin G Procaine for Inhalational Anthrax (Post-Exposure)
  • Public Health Emergency Home Preparation Instructions for Doxycycline 
    Includes the pamphlet, "In an Emergency: How to Prepare Doxycycline for Children and Adults Who Cannot Swallow Pills" (updated 7/2/2008)
  • Palatability Evaluations of Doxycycline Solid Dosage Tablets Ground and Mixed in Food or Drinks (7/3/2002)
  • Stability and Dose Uniformity Evaluations of Doxycycline Solid Dosage Tablets Ground and Mixed in Food or Drinks  (7/3/2002)
  • Doxycycline (Vibramycin, Monodox, Doryx, Doxy, Atridox, Periodox, Vibra-Tabs): Use by Pregnant and Lactating Women
  • Information for Consumers on Doxycycline
  • Information for Consumers on Penicillin G Procaine 
• Amoxicillin (Amoxil, Larotid, Trimox, Wymox) Use by Pregnant and Lactating Women  (11/20/2001) 
• Commentary on Non-Labeled Dosing of Oral Amoxicillin in Adults and Pediatrics for Post-Exposure Inhalational Anthrax  (12/17/2001) 

 
Chemical Agents

• Atropen (atropine autoinjector)
  FDA has approved new dosage forms of the Atropen for use in children and adolescents exposed to certain nerve agents or insecticides. The Atropen has been approved since 1973 for use in adults.  FDA Talk Paper (6/20/2003)

 
Radiation Emergencies

• Calcium-DTPA and Zinc-DTPA Information (For pediatric information, please view the labels.)
  Conditions under which calcium-DTPA (Ca-DTPA) and zinc-DTPA (Zn-DTPA) can be found to be safe and effective for the treatment of internal contamination with plutonium, americium, or curium to increase the rates of elimination of these substances from the body. (9/12/2003)  
• Potassium Iodide
  • Frequently Asked Questions on Potassium Iodide (KI)  (2/21/2002; updated 3/29/2011)
  • Home Preparation Procedure for Emergency Administration of Potassium Iodide Tablets to Infants and Small Children  (PDF - 33KB) (7/3/2002)
    • Easy-to-use, one-page instructions for home preparation of 130 mg tablets  (PDF - 329KB) (10/22/2002)
    • Easy-to-use, one-page instructions for home preparation of 65 mg tablets (PDF - 331KB) (10/22/2002) 
  • Guidance: Potassium Iodide as a Thyroid Blocking Agent in Radiation Emergencies (PDF - 40KB) (12/10/2001)
    Guidance on using potassium iodide to reduce the risk of thyroid cancer in children and adults in emergencies involving the release of radioactive iodine into the environment.
  • FDA Talk Paper: Guidance on Protection of Children and Adults Against Thyroid Cancer in Case of Nuclear Accident. (12/10/2001)
• Prussian Blue Information   
  FDA approved Radiogardase, also known as Prussian blue, to treat people exposed to radiation contamination, due to harmful levels of cesium-137 or thallium. (10/2/2003) 
  
  • Radiogardase (Prussian Blue) Labeling (PDF - 208KB) (prescribing information for children and adults)